Table 1.
Values of surviving fractions after 2 Gy only and combined treatments 2 Gy with hyperthermia (HT), PARP1-i, HSP90-i and DNA-PKcs-i.
| Cell Line | Sensitizing Agent | Surviving Fraction |
|---|---|---|
| SiHa | RT | 0.53 ± 0.08 |
| SiHa | RT + HT42 | 0.36 ± 0.10 |
| SiHa | RT + PARP1-i | 0.28 ± 0.09 |
| SiHa | RT + HT42 + PARP1-i | 0.16 ± 0.07 |
| SiHa | RT + HSP90-i | 0.58 ± 0.04 |
| SiHa | RT + HT42 + HSP90-i | 0.51 ± 0.05 |
| SiHa | RT + DNA-PKcs-i | 0.12 ± 0.03 |
| SiHa | RT + HT42 + DNA-PKcs-i | 0.03 ± 0.00 |
| HeLa | RT | 0.46 ± 0.03 |
| HeLa | RT + HT42 | 0.36 ± 0.09 |
| HeLa | RT + PARP1-i | 0.24 ± 0.08 |
| HeLa | RT + HT42 + PARP1-i | 0.10 ± 0.03 |
| HeLa | RT + HSP90-i | 0.56 ± 0.03 |
| HeLa | RT + HT42 + HSP90-i | 0.33 ± 0.04 |
| HeLa | RT + DNA-PKcs-i | 0.35 ± 0.06 |
| HeLa | RT + HT42 + DNA-PKcs-i | 0.16 ± 0.02 |