Table 3.
Fifty BANK1 tagging markers with association p value lower than 0.05, representing their respective linkage disequilibrium groups in the AA (African American) sample. (p *—p value conditioning on rs17200824; p **—p value conditioning on rs17200824, rs4295265, and rs149302668; A*—represents the allele used in the association analysis; HP.BK—haplotypic block; LK.GR—linkage disequilibrium group).
| HP.BK | LK.GR | CHR | MK.ID | BP | A1 | A2 | A* | F.ALL | F.CAS | F.CTR | NMISS | OR | L95 | U95 | p | p * | p ** |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| # | 1 | 4 | rs10031210 | 102714886 | A | G | 1 | 0.2233 | 0.2010 | 0.2479 | 2529 | 0.7563 | 0.6609 | 0.8655 | 4.92E−05 | 1.37E−01 | 7.25E−01 |
| 1 | 2 | 4 | rs4699262 | 102726005 | G | A | 2 | 0.1316 | 0.1090 | 0.1613 | 2520 | 0.6232 | 0.5271 | 0.7369 | 3.19E−08 | 1.36E−02 | 2.11E−01 |
| 1 | 3 | 4 | rs35828857 | 102729253 | A | AT | 2 | 0.1633 | 0.1393 | 0.1950 | 2465 | 0.6727 | 0.5774 | 0.7836 | 3.58E−07 | 3.52E−02 | 3.74E−01 |
| # | 4 | 4 | rs66638185 | 102729417 | T | C | 2 | 0.1658 | 0.1388 | 0.1974 | 2483 | 0.6574 | 0.5654 | 0.7643 | 4.92E−08 | 1.32E−02 | 3.26E−01 |
| 2 | 5 | 4 | rs13136796 | 102736743 | A | T | 2 | 0.3177 | 0.2929 | 0.3459 | 2494 | 0.7764 | 0.6883 | 0.8757 | 3.78E−05 | 4.88E−01 | 3.36E−01 |
| 2 | 6 | 4 | rs4615176 | 102737936 | C | G | 1 | 0.2351 | 0.2466 | 0.2205 | 2448 | 1.1790 | 1.0290 | 1.3510 | 1.81E−02 | 5.38E−01 | 3.50E−01 |
| 2 | 7 | 4 | rs1421627 | 102739536 | G | A | 2 | 0.4148 | 0.3953 | 0.4393 | 2529 | 0.8230 | 0.7345 | 0.9221 | 7.84E−04 | 6.58E−01 | 6.26E−01 |
| 2 | 8 | 4 | rs13136219 | 102743687 | C | T | 1 | 0.3893 | 0.4098 | 0.3623 | 2466 | 1.2320 | 1.0960 | 1.3850 | 4.70E−04 | 2.67E−01 | 2.10E−01 |
| # | 9 | 4 | rs13112246 | 102743811 | T | C | 2 | 0.4072 | 0.3826 | 0.4361 | 2475 | 0.8045 | 0.7179 | 0.9015 | 1.81E−04 | 8.76E−01 | 9.28E−01 |
| # | 10 | 4 | rs56857058 | 102749300 | A | AT | 1 | 0.3069 | 0.3208 | 0.2837 | 2515 | 1.2080 | 1.0690 | 1.3650 | 2.42E−03 | 3.29E−01 | 1.21E−01 |
| 3 | 11 | 4 | rs144220121 | 102750582 | G | GT | 2 | 0.1755 | 0.1895 | 0.1610 | 2478 | 1.2010 | 1.0320 | 1.3970 | 1.78E−02 | 3.04E−01 | 4.71E−01 |
| 3 | 12 | 4 | rs11938136 | 102750726 | G | A | 2 | 0.1027 | 0.1124 | 0.0925 | 2501 | 1.2240 | 1.0160 | 1.4750 | 3.31E−02 | 2.74E−01 | 3.51E−01 |
| 3 | 13 | 4 | rs17200824 | 102752589 | A | G | 2 | 0.2281 | 0.1984 | 0.2664 | 2516 | 0.6787 | 0.5947 | 0.7747 | 9.24E−09 | NA | NA |
| 3 | 14 | 4 | rs7438361 | 102756142 | G | A | 2 | 0.2143 | 0.2248 | 0.2000 | 2427 | 1.1570 | 1.0070 | 1.3290 | 3.96E−02 | 6.79E−01 | 7.94E−01 |
| # | 15 | 4 | rs72923462 | 102758014 | G | A | 2 | 0.0677 | 0.0725 | 0.0571 | 2427 | 1.2680 | 1.0070 | 1.5980 | 4.37E−02 | 2.21E−01 | 2.50E−01 |
| # | 16 | 4 | rs72923467 | 102760424 | G | A | 2 | 0.0810 | 0.0871 | 0.0692 | 2475 | 1.2780 | 1.0340 | 1.5780 | 2.29E−02 | 1.65E−01 | 1.32E−01 |
| 4 | 17 | 4 | rs4607219 | 102773838 | T | C | 1 | 0.2475 | 0.2619 | 0.2327 | 2473 | 1.1820 | 1.0370 | 1.3460 | 1.21E−02 | 6.01E−02 | 1.54E−01 |
| 4 | 18 | 4 | rs34166099 | 102778580 | C | A | 2 | 0.0427 | 0.0364 | 0.0510 | 2428 | 0.6751 | 0.5069 | 0.8993 | 7.23E−03 | 1.87E−01 | 8.52E−01 |
| 4 | 19 | 4 | rs4426778 | 102780724 | G | A | 1 | 0.2772 | 0.2893 | 0.2658 | 2512 | 1.1400 | 1.0060 | 1.2910 | 3.93E−02 | 2.07E−01 | 4.42E−01 |
| 4 | 20 | 4 | rs35201947 | 102781331 | C | T | 2 | 0.2026 | 0.1792 | 0.2329 | 2427 | 0.7211 | 0.6268 | 0.8297 | 4.87E−06 | 1.83E−01 | 7.15E−01 |
| 4 | 21 | 4 | rs34814827 | 102787117 | C | T | 2 | 0.3850 | 0.3661 | 0.4046 | 2513 | 0.8499 | 0.7589 | 0.9518 | 4.87E−03 | 5.13E−01 | 6.53E−01 |
| 4 | 22 | 4 | rs4493533 | 102820684 | C | T | 1 | 0.4461 | 0.4663 | 0.4251 | 2496 | 1.1790 | 1.0540 | 1.3190 | 3.99E−03 | 1.67E−01 | 5.78E−01 |
| 4 | 23 | 4 | rs34612070 | 102832696 | TC | T | 2 | 0.1222 | 0.1014 | 0.1469 | 2429 | 0.6586 | 0.5543 | 0.7826 | 2.07E−06 | 5.30E−02 | 5.63E−01 |
| 4 | 24 | 4 | rs4295265 | 102835645 | C | T | 2 | 0.1107 | 0.0897 | 0.1344 | 2444 | 0.6206 | 0.5161 | 0.7461 | 3.89E−07 | 4.97E−03 | NA |
| 5 | 25 | 4 | rs3733197 | 102839287 | G | A | 2 | 0.1827 | 0.1571 | 0.2150 | 2516 | 0.6762 | 0.5845 | 0.7824 | 1.44E−07 | 8.90E−03 | 9.33E−01 |
| 5 | 26 | 4 | rs13119516 | 102841605 | G | A | 2 | 0.0295 | 0.0238 | 0.0365 | 2505 | 0.6088 | 0.4325 | 0.8570 | 4.44E−03 | 1.96E−01 | 7.32E−01 |
| 5 | 27 | 4 | rs36073662 | 102841949 | G | GA | 2 | 0.3743 | 0.3584 | 0.3892 | 2485 | 0.8659 | 0.7716 | 0.9717 | 1.44E−02 | 5.73E−01 | 4.27E−01 |
| # | 28 | 4 | rs59723463 | 102857343 | G | GAT | 2 | 0.4205 | 0.4372 | 0.3982 | 2445 | 1.1740 | 1.0470 | 1.3150 | 5.89E−03 | 2.33E−01 | 5.17E−01 |
| # | 29 | 4 | rs2851336 | 102857563 | C | T | 2 | 0.4564 | 0.4414 | 0.4702 | 2452 | 0.8779 | 0.7830 | 0.9844 | 2.57E−02 | 5.68E−01 | 5.43E−01 |
| 6 | 30 | 4 | rs150123613 | 102879041 | G | A | 2 | 0.0114 | 0.0137 | 0.0081 | 2424 | 1.8240 | 1.0030 | 3.3170 | 4.88E−02 | 8.45E−02 | 1.10E−01 |
| 6 | 31 | 4 | rs72916176 | 102881821 | T | G | 2 | 0.1235 | 0.1335 | 0.1081 | 2432 | 1.2560 | 1.0530 | 1.4970 | 1.12E−02 | 1.06E−01 | 1.64E−01 |
| 6 | 32 | 4 | rs72929915 | 102890546 | A | G | 2 | 0.1616 | 0.1731 | 0.1451 | 2423 | 1.2110 | 1.0340 | 1.4180 | 1.75E−02 | 5.19E−02 | 1.44E−01 |
| 6 | 33 | 4 | rs976654 | 102898570 | A | C | 2 | 0.2763 | 0.2478 | 0.3088 | 2502 | 0.7336 | 0.6462 | 0.8328 | 1.69E−06 | 6.37E−03 | 2.29E−01 |
| 6 | 34 | 4 | rs1027013 | 102904490 | G | A | 2 | 0.1700 | 0.1433 | 0.2018 | 2526 | 0.6497 | 0.5581 | 0.7564 | 2.69E−08 | 6.41E−03 | 6.95E−01 |
| 6 | 35 | 4 | rs2851318 | 102915668 | A | T | 1 | 0.3250 | 0.3400 | 0.3107 | 2446 | 1.1450 | 1.0150 | 1.2920 | 2.76E−02 | 1.45E−01 | 6.21E−01 |
| 6 | 36 | 4 | rs6817137 | 102918724 | G | A | 2 | 0.1192 | 0.1299 | 0.1061 | 2496 | 1.2300 | 1.0300 | 1.4690 | 2.26E−02 | 1.91E−01 | 2.83E−01 |
| 6 | 37 | 4 | rs2903274 | 102919138 | T | C | 2 | 0.4800 | 0.4553 | 0.4940 | 2500 | 0.8204 | 0.7320 | 0.9195 | 6.71E−04 | 1.57E−02 | 2.34E−01 |
| 6 | 38 | 4 | rs6532981 | 102927216 | T | C | 2 | 0.2169 | 0.2314 | 0.2005 | 2470 | 1.1850 | 1.0320 | 1.3600 | 1.64E−02 | 8.45E−02 | 3.02E−01 |
| 6 | 39 | 4 | rs6532982 | 102927310 | A | G | 2 | 0.1763 | 0.1906 | 0.1593 | 2529 | 1.2200 | 1.0520 | 1.4150 | 8.47E−03 | 5.84E−02 | 1.72E−01 |
| # | 40 | 4 | rs1486571 | 102938040 | A | T | 1 | 0.1934 | 0.1725 | 0.2168 | 2415 | 0.7597 | 0.6538 | 0.8827 | 3.32E−04 | 4.79E−02 | 7.27E−01 |
| 7 | 41 | 4 | rs11412036 | 102942316 | G | GA | 1 | 0.0763 | 0.0626 | 0.0917 | 2419 | 0.6614 | 0.5320 | 0.8222 | 1.97E−04 | 3.86E−02 | 3.06E−01 |
| 7 | 42 | 4 | rs2850390 | 102943996 | A | C | 1 | 0.1462 | 0.1247 | 0.1693 | 2529 | 0.7007 | 0.5961 | 0.8237 | 1.62E−05 | 1.85E−02 | 6.68E−01 |
| 7 | 43 | 4 | rs2631268 | 102948730 | G | T | 2 | 0.3030 | 0.3151 | 0.2852 | 2530 | 1.1470 | 1.0150 | 1.2950 | 2.74E−02 | 5.63E−02 | 3.14E−01 |
| 7 | 44 | 4 | rs3133078 | 102952819 | C | A | 1 | 0.1673 | 0.1467 | 0.1890 | 2440 | 0.7383 | 0.6317 | 0.8628 | 1.36E−04 | 4.67E−02 | 7.79E−01 |
| 7 | 45 | 4 | rs149302668 | 102955310 | G | A | 2 | 0.0135 | 0.0114 | 0.0182 | 2507 | 0.6105 | 0.3773 | 0.9876 | 4.44E−02 | 2.91E−02 | NA |
| # | 46 | 4 | rs11326096 | 102968589 | CT | C | 1 | 0.3067 | 0.2886 | 0.3298 | 2436 | 0.8334 | 0.7370 | 0.9423 | 3.65E−03 | 1.92E−01 | 6.33E−01 |
| 8 | 47 | 4 | rs2850397 | 102970744 | G | T | 1 | 0.2362 | 0.2135 | 0.2629 | 2409 | 0.7759 | 0.6785 | 0.8873 | 2.10E−04 | 5.74E−02 | 4.17E−01 |
| 8 | 48 | 4 | rs2658535 | 102971016 | G | A | 1 | 0.3901 | 0.3674 | 0.4214 | 2454 | 0.8118 | 0.7237 | 0.9107 | 3.78E−04 | 6.30E−02 | 6.12E−01 |
| 8 | 49 | 4 | rs116552800 | 102974226 | A | G | 2 | 0.0386 | 0.0438 | 0.0318 | 2410 | 1.3840 | 1.0170 | 1.8840 | 3.88E−02 | 1.23E−01 | 2.06E−01 |
| # | 50 | 4 | rs2129292 | 102991139 | C | G | 1 | 0.3598 | 0.3400 | 0.3802 | 2418 | 0.8531 | 0.7572 | 0.9611 | 9.00E−03 | 1.03E−01 | 8.72E−01 |