. 2018 Aug 8;19(8):2331. doi: 10.3390/ijms19082331

Table 5.

The EUR–African Americans’ (AA) meta-analysis best signals for association located on the region comprising intron two, exon two, and intron three. In the EUR, the association best-hit coincided with haplotypic block two, containing linkage disequilibrium groups five and six; the AA the region was divided into three haplotypic blocks containing seven linkage disequilibrium groups (5, 6, 7, 8, 9 10, and 13). (A*—represents the allele used in the association analysis; FEM—fixed effect model).

MKID	BP	POS	EUR										AA								META
MKID	BP	POS	A1	A2	A*	H.B	L.G	N	F	F_CAS	F_CTR	P_val	A*	H.B	L.G	N	F	F_CAS	F_CTR	P_val	OR_EUR	OR_AA	OR_FEM	L95_FEM	U95_FEM	P_val	HetP_val
rs13136796	102736743	I2	A	T	2	2	6	8227	0.2874	0.2634	0.3123	7.36E−08	2	3	6	2494	0.3177	0.2929	0.3459	3.78E−05	0.8244	0.7764	0.8119	0.7641	0.8627	2.05E−11	0.31
rs66976837	102736943	I2	CTTGTT	C	2	2	6	8228	0.2874	0.2633	0.3124	6.66E−08	2	3	6	2495	0.3176	0.2929	0.3455	4.13E−05	0.8239	0.7774	0.8118	0.7640	0.8626	1.97E−11	0.32
rs10028805	102737250	I2	G	A	2	2	5	8277	0.3631	0.3384	0.3887	2.22E−09	1	3	8	2528	0.3930	0.4139	0.3665	4.72E−04	0.8177	0.8137	0.8167	0.7712	0.8648	4.33E−12	0.87
rs4615176	102737936	I2	C	G	2	2	5	8190	0.3699	0.3452	0.3955	2.33E−09	1	3	5	2448	0.2351	0.2466	0.2205	1.81E−02	0.8177	0.8482	0.8234	0.7759	0.8738	1.83E−10	0.43
rs4411998	102738147	I2	T	C	2	2	5	8213	0.3639	0.3395	0.3892	3.77E−09	1	3	8	2502	0.4029	0.4237	0.3763	6.26E−04	0.8198	0.8177	0.8193	0.7736	0.8677	9.57E−12	0.88
rs2052445	102738722	I2	A	G	2	2	6	8232	0.2877	0.2636	0.3126	7.45E−08	2	3	6	2495	0.3175	0.2926	0.3454	4.19E−05	0.8245	0.7777	0.8123	0.7645	0.8631	2.25E−11	0.32
rs5860695	102738856	I2	TA	T	2	2	6	8203	0.2882	0.2641	0.3132	7.84E−08	2	3	6	2495	0.3175	0.2926	0.3454	4.19E−05	0.8246	0.7777	0.8124	0.7645	0.8633	2.37E−11	0.32
rs35388091	102739452	I2	C	T	2	2	6	8255	0.2890	0.2648	0.3140	5.36E−08	2	3	7	2505	0.4146	0.3946	0.4381	9.61E−04	0.8229	0.8254	0.8236	0.7758	0.8743	2.06E−10	0.79
rs1421627	102739536	I2	G	A	2	2	6	8272	0.2899	0.2663	0.3143	9.40E−08	2	3	7	2529	0.4148	0.3953	0.4393	7.84E−04	0.8138	0.8230	0.8164	0.7686	0.8671	4.24E−11	0.88
rs13106926	102739791	I2	A	G	2	2	6	8070	0.2900	0.2654	0.3169	1.36E−08	2	3	6	2499	0.3180	0.2931	0.3458	4.12E−05	0.8243	0.7775	0.8121	0.7643	0.8629	2.14E−11	0.32
rs13107572	102739928	I2	C	A	2	2	6	8240	0.2879	0.2638	0.3127	7.19E−08	2	3	6	2498	0.3179	0.2929	0.3458	3.94E−05	0.8243	0.7770	0.8120	0.7642	0.8628	2.07E−11	0.32
rs13107612	102739980	I2	C	T	2	2	6	8240	0.2879	0.2638	0.3127	7.19E−08	2	4	6	2492	0.3186	0.2939	0.3461	5.06E−05	0.8226	0.7798	0.8115	0.7637	0.8623	1.80E−11	0.35
rs71597109	102741002	I2	C	T	2	2	6	8231	0.2894	0.2652	0.3144	5.27E−08	2	4	13	2494	0.2266	0.1969	0.2652	1.02E−08	0.8226	0.6786	0.7898	0.7423	0.8404	6.86E−14	0.02
rs13135381	102743353	I2	A	G	2	2	6	8211	0.2881	0.2637	0.3133	6.80E−08	2	4	13	2499	0.2267	0.1978	0.2643	2.27E−08	0.8278	0.6847	0.7941	0.7463	0.8450	2.62E−13	0.02
rs13136219	102743687	I2	C	T	2	2	5	8187	0.3661	0.3423	0.3909	8.21E−09	1	4	8	2466	0.3893	0.4098	0.3623	4.70E−04	0.8237	0.8117	0.8208	0.7750	0.8693	1.63E−11	0.77
rs55768089	102743698	I2	T	A	2	2	6	8212	0.2877	0.2641	0.3122	1.38E−07	2	4	13	2499	0.2267	0.1978	0.2643	2.27E−08	0.8274	0.6847	0.7938	0.7460	0.8447	2.37E−13	0.02
rs13112246	102743811	I2	T	C	2	2	5	8163	0.3662	0.3421	0.3912	9.33E−09	2	4	9	2475	0.4072	0.3826	0.4361	1.81E−04	0.8241	0.8045	0.8191	0.7736	0.8672	8.13E−12	0.61
rs13137133	102744092	I2	C	T	2	2	5	8205	0.3740	0.3512	0.3977	3.58E−08	1	4	10	2491	0.3050	0.3187	0.2817	2.68E−03	0.8312	0.8285	0.8306	0.7838	0.8802	3.49E−10	0.98
rs1125271	102745985	I2	C	T	2	2	6	8213	0.2877	0.2640	0.3122	1.27E−07	2	4	13	2505	0.2219	0.1924	0.2593	1.42E−08	0.8243	0.6794	0.7904	0.7427	0.8412	9.12E−14	0.02
rs4276281	102746780	I2	A	C	2	2	5	8252	0.3734	0.3505	0.3969	4.04E−08	1	4	10	2481	0.3020	0.3140	0.2795	9.75E−03	0.8318	0.8496	0.8357	0.7886	0.8856	1.40E−09	0.71
rs7698632	102747265	I2	G	C	2	2	5	8224	0.3724	0.3489	0.3968	1.54E−08	1	4	10	2511	0.3065	0.3202	0.2837	2.47E−03	0.8271	0.8278	0.8273	0.7807	0.8766	1.40E−10	0.93
rs12163856	102747927	I2	A	G	2	2	5	8159	0.3750	0.3514	0.3994	1.35E−08	1	4	10	2462	0.3538	0.3634	0.3351	1.89E−02	0.8266	0.8681	0.8362	0.7895	0.8856	1.01E−09	0.5
rs56857058	102749300	I2	A	AT	2	2	5	8213	0.3764	0.3530	0.4006	1.77E−08	1	4	10	2515	0.3069	0.3208	0.2837	2.42E−03	0.8282	0.8278	0.8281	0.7816	0.8774	1.58E−10	0.94
rs17266594	102750922	I2	T	C	2	2	6	8124	0.2863	0.2624	0.3109	1.25E−07	2	4	13	2514	0.2249	0.1962	0.2639	1.26E−08	0.8285	0.6795	0.7936	0.7459	0.8443	1.80E−13	0.01
rs10516487	102751076	E2	G	A	2	2	6	8220	0.2864	0.2624	0.3114	7.34E−08	2	4	13	2518	0.2232	0.1936	0.2604	1.41E−08	0.8273	0.6798	0.7929	0.7452	0.8437	1.53E−13	0.02
rs10516486	102751276	E2	T	C	2	2	5	8277	0.3761	0.3528	0.4002	1.30E−08	1	4	10	2530	0.3089	0.3218	0.2866	3.47E−03	0.8269	0.8333	0.8283	0.7818	0.8775	1.66E−10	0.85
rs34029191	102752201	I3	A	G	2	2	6	8237	0.2912	0.2676	0.3155	1.38E−07	2	4	13	2517	0.2275	0.1981	0.2655	1.22E−08	0.8270	0.6804	0.7924	0.7448	0.8431	1.32E−13	0.02
rs17200824	102752589	I3	A	G	2	2	6	8233	0.2887	0.2651	0.3131	1.15E−07	2	4	13	2516	0.2281	0.1984	0.2664	9.24E−09	0.8268	0.6787	0.7919	0.7444	0.8424	9.88E−14	0.01
rs4637409	102753408	I3	A	G	2	2	6	7966	0.2809	0.2565	0.3062	1.04E−07	2	4	13	2527	0.2221	0.1937	0.2604	1.12E−08	0.8264	0.6771	0.7917	0.7441	0.8424	1.05E−13	0.02
rs34749007	102754507	I3	G	A	2	2	6	8239	0.2889	0.2653	0.3133	1.09E−07	2	4	13	2469	0.2313	0.2033	0.2670	1.05E−07	0.8265	0.6977	0.7961	0.7480	0.8473	6.18E−13	0.04
rs5860696	102755799	I3	CA	C	2	2	5	8004	0.3603	0.3351	0.3863	2.52E−09	1	5	8	2422	0.3906	0.4119	0.3643	8.05E−04	0.8165	0.8183	0.8169	0.7709	0.8656	8.07E−12	0.95
rs4643809	102756099	I3	C	T	2	2	5	8038	0.3611	0.3362	0.3869	5.03E−09	1	5	8	2409	0.3844	0.4051	0.3574	7.77E−04	0.8202	0.8163	0.8193	0.7732	0.8682	1.56E−11	0.89