Table 2.
Inhibitors | Disease | RESPONSE | Reference |
---|---|---|---|
CC-115 | R/R CLL | PR | Thijssen, et al. [120] |
Rapamycin + NVP-BEZ235 | ALL | Increase apoptosis | Messina, et al. [108] |
RAD001, Torin-2 and CCI-779 | ALL | Increase apoptosis | Bertacchini, et al. [83] |
Imatinib + mTOR inhibitor | Imatinib-resistant Ph + ALL | Increase apoptosis | Xing H., et al. [109] |