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. 2018 Aug 14;19(8):2396. doi: 10.3390/ijms19082396

Table 2.

mTOR inhibitors in lymphoid leukemias.

Inhibitors Disease RESPONSE Reference
CC-115 R/R CLL PR Thijssen, et al. [120]
Rapamycin + NVP-BEZ235 ALL Increase apoptosis Messina, et al. [108]
RAD001, Torin-2 and CCI-779 ALL Increase apoptosis Bertacchini, et al. [83]
Imatinib + mTOR inhibitor Imatinib-resistant Ph + ALL Increase apoptosis Xing H., et al. [109]