Table 3.

Associations Between Predictors Other Than Exposure to Proton Pump Inhibitors and Study Outcomes

	Outcome, HR (95% CI)
Predictor	Death	Death or Rehospitalization
Age	1.06(1.01–1.11)	1.00 (0.95–1.03)
Sex	0.72 (0.42–1.22)	1.00 (0.66–1.50)
BMI <20	1.01 (0.96–1.07)	1.01 (0.97–1.06)
Hypoalbuminemia	2.36 (1.31–4.25)	1.65 (1.10–2.46)
MMSE score <24	1.04 (0.52–2.05)	1.06 (0.66–1.70)
Complete dependency	7.41 (3.64–15.10)	4.51 (2.58–7.90)
in ADLs
CIRS comorbidity	1.10 (1.03–1.24)	1.16 (1.04–1.30)
score
Cardiovascular	1.77 (0.42–2.43)	1.67 (0.62–3.06)
disease
GERD	1.62 (0.70–3.72)	1.55 (0.87–2.78)
Peptic ulcer	1.98 (0.83–6.60)	1.84 (0.79–5.57)
Diarrhea	1.80 (0.40–8.18)	2.32 (0.54–9.98)
Infectious disease	1.66 (0.33–2.30)	1.87 (0.50–3.53)
Fracture	1.77 (0.11–6.98)	1.60 (0.40–3.56)
No. of drugs	0.98 (0.88–1.07)	1.04 (0.96–1.12)
prescribed at discharge
Antithrombotic use	0.59 (0.33–0.99)	0.70 (0.43–1.03)
NSAID use	0.90 (0.19–3.77)	0.97 (0.37–2.90)

Abbreviations: ADLs, activities of daily living; BMI, body mass index (calculated as weight in kilograms divided by height in meters squared); CiRS, Cumulative Illness Rating Scale; GERD, gastroesophageal reflux disease; HR, hazard ratio; MMSE, Mini-Mental State Examination; NSAID, nonsteroidal anti-inflammatory drugs.