Table 2.
Compd | MIC [μg mL−1] | CC50 [μg mL−1][a] | SI[b] | ||
---|---|---|---|---|---|
HEK293T | HepG2 | HEK293T | HepG2 | ||
5 | 1 | 20.6 | 36.8 | 20.6 | 36.8 |
6 | 1 | 26.5 | 31.7 | 26.5 | 31.7 |
8 | 1 | 33.9 | 30.1 | 33.9 | 30.1 |
9 | 2 | 42.7 | 40.3 | 21.35 | 20.15 |
11 | 2 | 25.1 | 24.0 | 12.55 | 12 |
12 | 1 | 32.3 | 33.1 | 32.3 | 33.1 |
13 | 1 | 31.8 | 37.3 | 31.8 | 37.3 |
14 | 1 | 29.3 | 26.8 | 29.3 | 26.8 |
15 | 1 | 25.7 | 25.9 | 25.7 | 25.9 |
16 | 1 | 24.3 | 18.1 | 24.3 | 18.1 |
50% cytotoxic centration.
Selectivity index: CC50/MIC.