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. Author manuscript; available in PMC: 2018 Sep 4.
Published in final edited form as: ChemMedChem. 2018 Jun 14;13(14):1414–1420. doi: 10.1002/cmdc.201800240

Table 2.

Cytotoxicity assessment of active compounds (MIC <4 μg mL−1).

Compd MIC [μg mL−1] CC50 [μg mL−1][a] SI[b]
HEK293T HepG2 HEK293T HepG2
5 1 20.6 36.8 20.6 36.8
6 1 26.5 31.7 26.5 31.7
8 1 33.9 30.1 33.9 30.1
9 2 42.7 40.3 21.35 20.15
11 2 25.1 24.0 12.55 12
12 1 32.3 33.1 32.3 33.1
13 1 31.8 37.3 31.8 37.3
14 1 29.3 26.8 29.3 26.8
15 1 25.7 25.9 25.7 25.9
16 1 24.3 18.1 24.3 18.1
[a]

50% cytotoxic centration.

[b]

Selectivity index: CC50/MIC.