Table 3.

Association (Odds Ratio, OR and 95% confidence intervals, CI) of disability in the activities of daily living at baseline according to the initial (age-and sex-adjusted), and “summary” (fully adjusted) logistic regression models in 545 participants aged above the median value (74 yrs). All the covariates were entered simultaneously into the regression models.

	Age- and sex-adjusted models			Summary model
	OR	95% CI	p	OR	95% CI	p
Demographics & lifestyle habits
Age (years)	1.14	1.03–1.27	.015	1.13	1.08–1.19	<.0001
Sex (female)	1.63	.40–6.67	.498	1.60	.87–2.95	.132
Education (years)	.92	.71–1.17	.491
Current alcohol consumptiona	1.01	.94–1.08	.832
Smokingb	1.01	.98–1.04	.498
Protein consumption (g/Kg/day)	2.33	.03–16.88	.698
Total lipids consumption (g/Kg/day)	2.72	.01–18.06	.718
Carbohydrates consumption (g/Kg/day)	2.62	.43–16.12	.299
Total energy (kcal/Kg/day)	.83	.53–1.30	.409
Comorbid conditions
Chronic pulmonary disease	.72	.25–2.06	.541
Heart failure	.83	.29–2.37	.727
Stroke	1.20	.48–3.01	.690
Arthritis	.42	.14–1.27	.125
Parkinson's disease	5.11	1.29–20.21	.020	5.24	1.35–20.34	.017
Peripheral arterial disease	.50	.21–1.20	.122
Coronary disease	.28	.07–1.10	.069
Charlson comorbidity score index	1.97	1.51–2.56	<.0001	1.80	1.48–2.19	<.0001
Metabolic syndrome	.37	.15–.90	.027	.33	.14–.77	.010
Medications
Beta-blockers	.86	.11–6.80	.885
Corticosteroids	.52	.06–4.13	.534
ACE-Ic	.93	.47–1.86	.841
Loop diuretics	1.53	.74–3.13	.249
NSAIDs	1.20	.15–9.61	.865
Antiplatelets	1.24	.64–2.42	.527
Objective tests
Total proteins (g/dl)	1.44	.11–18.16	.780
Serum creatinine (mg/dl)	3.81	.02–67.89	.613
Interleukin 6 (pg/ml)	.99	.24–4.05	.994
CRP-HS (mgml)d	.50	.13–1.98	.325
Mini Mental State Examination	.73	.52–1.03	.072
CES-De	1.11	.99–1.23	.066
Body mass index	1.07	.83–1.40	.592
Hemoglobin (g/dL)	3.31	.85–12.96	.086
Handgrip (Kgs)	.85	.72–1.01	.065

^aNumber of weekly wine glasses.

^bTotal lifetime pack years.

^cAngiotensin-Converting Enzyme inhibitors.

^dLog–transformed.

^e20-item version of the Center for Epidemiological Studies-Depression Scale.