Table 1.
Baseline characteristics of community-dwelling frail older patients with coronary artery disease (CAD) divided according to their Multidimensional Prognostic Index (MPI) risk group based on the Standardized Multidimensional Assessment Schedule for Adults and Aged Persons (SVaMA)
| Variable | All | MPI-SVaMA-1 Mild risk |
MPI-SVaMA-2 Moderate risk |
MPI-SVaMA-3 Severe risk |
p-value (test for trend) |
|---|---|---|---|---|---|
| Patients (%) | 2597 (100%) | 785 (30.2%) | 1096 (42.2%) | 716 (27.6%) | — |
| Age at SVaMA evalutation (years) | 83.93±7.35 | 81.94±7.34 | 84.74±7.21 | 84.87±7.15 | <0.001 |
| Sex n males (%) | 1155 (44.47%) | 249 (31.72%) | 452 (41.24%) | 454 (63.41%) | <0.001 |
| Activities of daily living | 42.50±18.64 | 21.64±14.72 | 47.85±13.00 | 57.17±5.26 | <0.001 |
| Cognitive status | 5.20±3.60 | 3.41±3.13 | 5.24±3.43 | 7.10±3.32 | <0.001 |
| Nursing care needs | 7.88±8.42 | 2.82±4.69 | 6.20±6.35 | 15.99±8.58 | <0.001 |
| Mobility | 30.55±11.85 | 17.01±11.03 | 34.67±6.84 | 39.10±2.15 | <0.001 |
| Pressure sore risk | 5.05±6.26 | 0.14±1.28 | 4.33±5.27 | 11.55±5.30 | <0.001 |
| Social support | 159.59±70.01 | 142.08±70.69 | 163.59±67.77 | 172.66±68.93 | <0.001 |
| Number of medications* | 41.42±59.86 | 46.07±62.18 | 40.74±59.35 | 37.36±57.75 | 0.003 |
| Main associated diagnoses | |||||
| Fractures | 44 (1.69%) | 13 (1.66%) | 21 (1.92%) | 10 (1.40%) | <0.001 |
| Cancer | 419 (16.13%) | 122 (15.54%) | 170 (15.51%) | 127 (17.74%) | |
| Dementia | 583 (22.45%) | 182 (23.18%) | 271 (24.73%) | 130 (18.16%) | |
| Stroke | 173 (6.66%) | 34 (4.33%) | 67 (6.11%) | 72 (10.06%) | |
| Cardiovascular disease | 615 (23.68%) | 226 (28.79%) | 254 (23.18%) | 135 (18.85%) | |
| Respiratory disease | 81 (3.12%) | 20 (2.55%) | 31 (2.83%) | 30 (4.19%) | |
| Neurologic disease | 110 (4.24%) | 43 (5.48%) | 38 (3.47%) | 29 (4.05%) | |
| Hypokinetic syndrome | 326 (12.55%) | 57 (7.26%) | 154 (14.05%) | 115 (16.06%) | |
| Other diseases | 246 (9.47%) | 88 (11.21%) | 90 (8.21%) | 68 (9.50%) | |
| Follow-up time (years) | 2.05±2.24 | 2.81±2.53 | 2.04±2.14 | 1.24±1.68 | <0.001 |
| Mortality at 1 year ev/py (ir %)† | 1081/1765 (61.2%) | 217/619 (35.1%) | 431/771 (55.9%) | 433/375 (115.4%) | <0.001 |
| Mortality at 2 years ev/py (ir %)† | 1336/2941 (45.4%) | 283/1079 (26.2%) | 543/1282 (42.4%) | 510/579 (88.0%) | <0.001 |
| Mortality at 3 years ev/py (ir %)† | 1519/3789 (40.1%) | 338/1442 (23.4%) | 641/1638 (39.1%) | 540/709 (76.2%) | <0.001 |
*
Number of all medications per month, taken before the patient’s enrollment.
†
ev/py: events/person-years, ir %: incidence rate (number of events per 100 person-years).