Table 1.
Classification of higher order repeat (HOR) alpha satellite arrays on human chromosomes.
| Chrom | Array/Locus Name |
Ucsc designation |
SF | HOR size (kb) |
HOR Monomer # |
Total array size (Mb)* |
Centromere Function | |||
|---|---|---|---|---|---|---|---|---|---|---|
| HAC assay |
CENP ChlPa |
CENP IFa |
Epiallele | |||||||
| 1 | D1Z7b | cen1.1_cen5.2_cen19.3 | 1 | 0.34 | 2 | 0.4–1.1 | n.d. | yes | yes | yes |
| 1 | D1Z5 | cen1.2 | 3 | 1.9 | 11 | 0.4–1.5 | n.d. | yes | yes | yes |
| 2 | D2Z1 | cen2.1 | 2 | 1.4 | 8 | 1.0–2.9 | n.d. | yes | yes | n.a. |
| 3 | D3Z1 | cen3.1 | 1 | 2.9 | 17 | 1.0–3.1 | n.d. | yes | yes | n.a. |
| 4 | D4Z1 | cen4.1 | 2 | 3.2 | 19 | 2.3–4.4 | n.d. | yes | yes | n.a. |
| 5 | D5Z1c | cen5.1 | 5 | 2.2 | 13 | n.d. | no | no | no | n.d. |
| 5 | D5Z2b | cen5.2_cen1.1_cen19.3 | 1 | 0.34 | 2 | n.d. | n.d. | yes | yes | n.d. |
| 6 | D6Z1 | cen6.1 | 1 | 3.0 | 18 | 2.3–37 | n.d. | yes | yes | n.a. |
| 7 | D7Z1 | cen7.1 | 1 | 1.0 | 6 | 1.5–3.8 | n.d. | yes | yes | yes |
| 7 | D7Z2 | cen7.2 | 5 | 2.7 | 16 | 0.1 −0.6 | yes | yes | yes | yes |
| 8 | D8Z2 | cen8.1 | 2 | 1.9 | 11 | 1.5–2.2 | n.d. | yes | yes | n.d. |
| 9 | D9Z4 | cen9.1 | 2 | 1.2 | 7 | 1.8–2.2 | n.d. | yes | yes | n.a. |
| 10 | D10Z1 | cen10.1 | 1 | 1.4 | 8 | 1.4–2.5 | n.d. | yes | yes | n.a. |
| 10 | D10Z? | cen10.2 | 1 | 3.0 | 18 | n.d. | n.d. | n.d. | n.d. | n.d. |
| 11 | D11Z1 | cen11.1 | 3 | 0.85 | 5 | 1.8–4.8 | yes | yes | yes | n.d. |
| 11 | D11Z? | cen11.2 | 3 | 2.0 | 12 | n.d. | n.d. | n.d. | n.d. | n.d. |
| 12 | D12Z3 | cen12.1 | 1 | 1.4 | 8 | 2.2–4.3 | n.d. | yes | yes | n.a. |
| 13 | D13Z1d | cen13.1_cen21.1 | 2 | 1.9 | 11 | 1.1 −3.0 | n.d. | yes | yes | n.a. |
| 14 | D14Z9e | cen14.2_cen22.1 | 2 | 1.4 | 8 | 2.0 (avg) | n.d. | yes | yes | n.a. |
| 15 | D15Z3 | cen15.1 | 5 | 2.4 | 14 | 0.1 −0.8 | n.d | no | no | n.d. |
| 15 | D15Z4 | cen15.2 | 2 | 4.4 | 26 | 1.1 −2.7 | n.d. | yes | yes | n.d. |
| 16 | D16Z2 | cen16.1 | 1 | 1.7 | 10 | 0.4–2.0 | n.d. | yes | yes | n.d |
| 17 | D17Z1 | cen17.1 | 3 | 2.7 | 16 | 1.1 −4.2 | yes | yes | yes | yes |
| 17 | D17Z1-B | cen17.2 | 3 | 2.4 | 14 | 0.5–1.5 | yes | yes | yes | yes |
| 17 | D17Z1-C | cen17.3 | 3 | 2.4 | 14 | 0.5–1.5 | n.d. | no | yes | n.d. |
| 18 | D18Z1 | cen18.1 | 2 | 2.0 | 12 | 1.3–2.5 | n.d. | yes | yes | n.d. |
| 18 | D18Z2 | cen18.2 | 2 | 1.7 | 10 | 0.4–2.8 | n.d. | no | no | n.d. |
| 19 | D19Z1c | cen19.1_cen5.1 | 5 | 2.9 | 17 | n.d. | no | no | no | n.d. |
| 19 | D19Z3b | cen19.3_cen1.1_cen5.2 | 1 | 0.34 | 2 | n.d. | n.d. | yes | yes | n.d. |
| 20 | D20Z1 | cen20.1 | 2 | 2.7 | 16 | n.d. | n.d. | n.d. | n.d. | n.d. |
| 20 | D20Z2 | cen20.2 | 2 | 1.0 | 6 | 0.5–1 | n.d. | yes | yes | n.d. |
| 21 | D21Z1d | cen21.1_cen13.1 | 2 | 1.9 | 11 | o CO I o |
yes | yes | yes | n.a. |
| 22 | D22Z1e | cen22.1_cen14.2 | 2 | 1.4 | 8 | n.d. | n.d. | yes | yes | n.d. |
| 22 | D22Z2 | cen22.2 | 2 | 2.0/2.7 | 12/16 | 2.0 (avg) | n.d. | yes | yes | n.d. |
| X | DXZ1 | cenX.1 | 3 | 2.0/2.2 | 12/13 | 1.3–4.2 | yes | yes | yes | n.a. |
| Y | DYZ3 | cenY.1 | 4 | 5.8 | 34 | 0.2–1.2 | no | yes | yes | n.a. |
*
sizes compiled from the literature using pulsed-field gel electrophoresis-Southern blotting, quantitative FISH, and/or sequence reads;
a
on endogenous chromosomes
b
share the same HOR sequence
c
share the same HOR sequence
d
share same HOR sequence
e
share same HOR sequence
n.a., not applicable
n.d., not determined