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. Author manuscript; available in PMC: 2019 Sep 4.
Published in final edited form as: J Am Coll Cardiol. 2018 Sep 4;72(10):1109–1122. doi: 10.1016/j.jacc.2018.06.049

Figure 2. Association of rapid decline in FVC with incident cardiovascular disease.

Figure 2

Rapid decline is defined as greatest quartile of decline in FVC over a mean of 2.9 years. Kaplan-Meier curves demonstrate the rates of (A) incident heart failure, (B) incident coronary heart disease, (C) incident stroke, and (D) the composite of these among the rapid decliner and non-rapid decliner groups. Hazard ratios (HR) and associated 95% confidence intervals are calculated from Cox regression models adjusted for age, sex, race, ARIC center, height, heart rate, body mass index, LDL-cholesterol, NT-proBNP, diabetes, hypertension, and smoking.