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. Author manuscript; available in PMC: 2019 Sep 4.
Published in final edited form as: J Am Coll Cardiol. 2018 Sep 4;72(10):1109–1122. doi: 10.1016/j.jacc.2018.06.049

Table 4.

Risk of heart failure associated with rapid decline in lung function defined based on percentage of predicted FEV1 stratified by follow-up time (≤ or > 1 year or 10 years)

≤1 year p > 1 year p ≤10 year p > 10 year p




Events HR (95%CI) Events HR (95%CI) Events HR (95%CI) Events HR (95%CI)
22 4.22 (1.34–13.26) 0.014 1451 1.16 (1.02–1.31) 0.023 445 1.47 (1.18–1.83) 0.001 1028 1.07 (0.92–1.24) 0.40

FEV1: forced expiratory volume in 1 s; HR (95%CI): hazard ratio and 95% confidence interval. HRs are from a fully adjusted Model 3: baseline FEV1, age, sex, race, height, ARIC center, body mass index, heart rate, low-density-lipoprotein cholesterol, lipid-lowering medication, NT-proBNP, diabetes, hypertension, and smoking.