Table 2.
Cox Proportional Hazards Analysis in Patients With an Estimated Glomerular Filtration Rate Greater Than 40 mL/min/1.73 m2
| Parameter | Parameter Estimate |
P Value |
HR (95% CI) |
|---|---|---|---|
| Log(suPAR) | 1.633 | .007 | 5.122 (1.574–16.665) |
| eGFR | −0.048 | .006 | 0.952 (0.920–0.986) |
| Sex | |||
| Female vs male | 0.282 | .39 | 1.326 (0.698–2.520) |
| Age, y | 0.081 | .09 | 1.084 (0.988–1.190) |
| Proteinuria | |||
| Yes | 1.021 | .003 | 2.775 (1.408–5.469) |
| Systolic BP | |||
| SDS | −0.019 | .88 | 0.981 (0.765–1.257) |
| Primary renal diagnosis | |||
| Other CAKUT | 1 [Reference] | NA | NA |
| CAKUT, refluxive/obstructive | −0.735 | .07 | 0.479 (0.219–1.051) |
| Glomerulopathies | 1.618 | <.001 | 5.047 (2.089–12.189) |
| Post-AKI | −1.394 | .18 | 0.248 (0.032–1.904) |
| Tubulointerstitial disease | 0.643 | .24 | 1.903 (0.654–5.534) |
| Other | −0.212 | .74 | 0.809 (0.230–2.850) |
Abbreviations: AKI, acute kidney injury; BP, blood pressure; CAKUT, congenital anomalies ofthe kidneysand urinarytract; eGFR, estimatedglomerular filtration rate; HR, hazard ratio; NA, not applicable; SDS, standard deviation score; suPAR, soluble urokinase receptor.