Table 1.

[⁶⁸Ga]Ga-DOTA Radiolabeling Yields in Percentage (%) and Normalized (in Square Brackets) Values Relative to the Radiochemical Yields Obtained at 70 °C in a Pure Aqueous Solution and in Mixtures with Various Organic Solvents (30 vol%) with 10 nmol of DOTA Depending on the Reaction Time^a

time (min)	radiolabeling yields (%) and factors of increase (in square brackets)
	H2O	EtOH	MeCN	iPrOH
1	5.7 ± 1.1 [1]	9.0 ± 0.7 [1.6]	6.7 ± 0.4 [1.2]	12.0 ± 1.3 [2.1]
3	13.7 ± 2.2 [1]	42.7 ± 3.8 [3.1]	51.3 ± 2.2 [3.7]	63.3 ± 2.4 [4.6]
5	21.0 ± 2.0 [1]	68.3 ± 2.2 [3.3]	71.0 ± 1.3 [3.4]	74.7 ± 0.9 [3.6]
10	51.0 ± 3.3 [1]	79.7 ± 0.4 [1.6]	81.3 ± 0.4 [1.6]	82.3 ± 0.4 [1.6]
15	66.3 ± 2.9 [1]	84.0 ± 0.7 [1.3]	83.7 ± 0.9 [1.3]	86.7 ± 0.4 [1.3]

^aThe dramatic increase observed for a short reaction time, such as 3 min, is indicated in boldface.