Table 3.
Drugs of PPAR ligands for type 2 diabetes treatment in clinical stage.
| Generic Name | Type of PPAR Agonist | Molecular Weight | Company | Development Status |
|---|---|---|---|---|
| Chiglitazar | PPARs agonist | 594.61 | ChipScreen | Phase Ш active |
| KDT-501 | PPARα agonists | 404.588 | KinDex Pharmaceuticals | Phase II active |
| Naveglitazar | PPAR modulator | 422.477 | Lilly(Originator)Ligand (Originator) | Phase II Pending |
| AVE-0897 | Dual PPARα/γ agonist | 469 | Genfit(Originator)Sanofi | Phase І active |
| ZY-H2 | Dual PPARα/γ agonist | unknown | Zydus cadila | Phase І Pending |