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. 2018 Jul 14;59(9):1695–1708. doi: 10.1194/jlr.M087056

Fig. 2.

Fig. 2.

HFD feeding initially induces rapid weight loss, whereas chronic HFD feeding reduces weight gain, in CTαIKO mice. A: Body mass change relative to total body mass at time of initiation of the HFD; graph is representative of two independent experiments (n = 12 control and 14 CTαIKO mice). Visceral fat mass (B), plasma leptin concentrations (C), and liver TG (D) of control and CTαIKO mice on day 6 following initiation of the HFD (n = 6 per group). E: Body mass of control and CTαIKO mice on days 0 and 50 after initiation of the HFD (n = 5 per group). Visceral fat mass (F) and blood glucose concentrations (G) of control and CTαIKO mice on day 50 after initiation of the HFD (n = 5 per group). Fasting plasma TG (H) and fasting plasma cholesterol (I) concentrations of control mice and CTαIKO mice on days 6 and 50 after initiation of the HFD (n ≥ 5 per group). All mice were female. Values are means ± SEM. * P < 0.05; **** P < 0.0001.