Fig. 3.
CTαIKO mice fed a HFD have impaired intestinal TG secretion after a meal. Control and CTαIKO mice were fasted overnight and refed the HFD for 2 h. A: Plasma TG, NEFAs, and cholesterol after refeeding (n = 10 per group). B: FPLC of plasma lipoprotein TG after refeeding (pooled plasma samples from n = 5 per group). C: Representative immunoblot of plasma apolipoproteins after refeeding (ApoB and ApoA1 were run on separate gels). D: FPLC of plasma lipoprotein cholesterol after refeeding (pooled plasma samples from n = 5 per group). E: Plasma TG before and 1, 2, 3, and 4 h following an oral bolus of olive oil and intraperitoneal injection of Poloxamer-407 (n = 4 per group). All mice were female. Values are means ± SEM. * P < 0.05; **** P < 0.0001.