Table 1.
From functional analysis using gene ontology, 4 autophagy-regulating genes (FBXL2, HTR2B, MAPT, RAB33A) were found downregulated and 3 (HK2, SOGA3, BNIP3) upregulated in the old cells compared to their young counterpart (p > 0.05).
| Autophagy-Regulating Genes Downregulated in the Old Cells | ||
| OLD/YOUNG. fc | p-value | |
| FBXL2 | −4.021224 | >0.05 |
| HTR2B | −2.349009 | >0.05 |
| MAPT | −4.279171 | >0.05 |
| RAB33A | −5.610289 | >0.05 |
| Autophagy-Regulating Genes Upregulated in the Old Cells | ||
| OLD/YOUNG. fc | p-value | |
| HK2 | 2.100391 | >0.05 |
| SOGA3 | 2.114569 | >0.05 |
| BNIP3 | 2.776557 | >0.05 |