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. Author manuscript; available in PMC: 2018 Sep 25.
Published in final edited form as: N Engl J Med. 2018 Sep 26;379(15):1403–1415. doi: 10.1056/NEJMoa1800474

Table 1. Number of isolates by country and drug resistance profile.

Country of sample origin Time period of isolation Enriched for resistance Susceptible to all 4 drugs Susceptible to 3 drugs, with missing pyrazinamide result Isoniazid resistant, rifampicin susceptible Isoniazid susceptible, rifampicin resistant Isoniazid resistant, rifampicin resistant Other pattern Total
Australia 2006-2016 Yes 0 0 4 0 38 0 42
Belgium 2007-2015 Yes 121 0 2 0 97 14 234
Canada 2003-2014 Yes 11 1,118 164 14 24 12 1343
China 2009-2012 Yes 0 44 0 0 236 0 280
Germany 1998-2015 No 248 0 9 1 13 2 273
Italy 2008-2016 Yes and No* 82 1 9 0 132 2 226
Netherlands 1993-2016 No 420 42 24 1 149 31 667
Pakistan 2014-2015 Yes 47 5 11 6 345 1 415
Peru 1997-2009 Yes 24 12 49 18 199 13 315
Russia 2008-2010 Yes 282 0 116 15 407 22 842
Serbia 2008-2014 Yes 0 0 0 0 105 0 105
South Africa 2012-2014 Yes 593 11 37 69 151 130 991
Spain 2013-2015 Yes 45 3 5 2 8 1 64
Swaziland 2009-2010 Yes 2 130 14 4 116 7 273
Thailand 1998-2013 Yes 0 53 7 4 188 0 252
UK 2009-2017 Yes and No* 3,036 82 167 6 442 154 3,887
Total 4911 1501 618 140 2650 389 10209
*

More than one collection was derived from Italy and the UK, some enriched and some not enriched for resistance. See supplement for details.