TABLE 1.

MIC testing of ST55 and ST4 E. faecalis strains isolated from macaques 1 and 2 over time

Macaque	Mo and yr of isolate collection	ST	MIC (μg/ml)a
			Ampicillin	Bacitracin	Enrofloxacin	Erythromycin	Gentamicin	Neomycin	Streptomycin	Tetracycline
1	Aug. 2011	55	1–2	>128	1	>64	16–64	>2,048	>2,048	64
	May 2014	55	1	>128	1	>64	32	>2,048	>2,048	64
	March 2015	55	1	>128	1	>64	32	>2,048	>2,048	64
2	Aug. 2011	4	1–2	8–16	64	0.25	8–16	128	>2,048	128–256
	April 2014	4	1	4	64	0.25	16	256	>2,048	256
	May 2016	4	1	8	64	0.5	16–32	2,048	>2,048	256
CLSI resistance breakpoints			≤16	NA	NA	≥8	Low-level IR; HLAR, >500	Low-level IR; HLAR, NA	Low-level IR; HLAR, >1,000	≥16

^aCLSI resistance breakpoints are described elsewhere (45, 46). The MIC of povidone-iodine was 0.3125% for all isolates tested; a CLSI resistance breakpoint is not available for povidone-iodine. NA, not available; IR, intrinsic resistance; HLAR, high-level aminoglycoside resistance.