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. 2018 Aug 31;84(18):e00914-18. doi: 10.1128/AEM.00914-18

TABLE 5.

Associations between alpha diversity (number of OTUs and Shannon index) and variables related to demography, change in feeding mode, and antibiotic use at 12 months (n = 68)

Predictor variable No. of OTUs
Shannon index
Mean difference per unit of predictor variablea (95% CI) P valueb Mean difference per unit of predictor variablea (95% CI) P valueb
Parity (no. of children) 23.5 (9.5, 37.5) 0.001 0.31 (0.12, 0.49) 0.002
Mode of delivery (caesarian section compared to vaginal birth) 14.1 (−19.2, 47.4) 0.401 0.17 (−0.27, 0.61) 0.440
Maternal education (having university degree compared to not having one) 0.3 (−28.9, 29.5) 0.983 −0.03 (−0.41, 0.36) 0.890
Household deprivation (deprivation category) −13.6 (−34.0, 6.9) 0.189 −0.10 (−0.37, 0.17) 0.473
Consumption of infant formula (had consumed compared to had not) 24.2 (−5.2, 53.7) 0.105 0.12 (−0.28, 0.52) 0.547
Age at introduction of infant formula (wk) 0.7 (−0.5, 1.9) 0.265 0.01 (−0.002, 0.03) 0.098
Age at introduction of solids (wk) −3.2 (−8.5, 2.1) 0.237 −0.03 (−0.10, 0.04) 0.450
Age at introduction of infant cereal (wk) 0.7 (−2.6, 3.9) 0.688 −0.002 (−0.04, 0.04) 0.931
Infant antibiotic use at time of fecal sample (had consumed compared to had not) 15.9 (−29.2, 61.1) 0.483 0.29 (−0.30, 0.88) 0.333
a

Unless otherwise indicated. Shown is linear regression with adjustment for group.

b

Boldface indicates statistically significant differences between variables.