. 2018 May 18;54(3):32. doi: 10.3390/medicina54030032

Table 2.

Comparison of allele and genotype frequencies of two MAOA gene polymorphisms between ADHD children and controls.

	Allele/Genotype	ADHD-Boys	Control-Boys	p-Value ^a	OR (95% CI)
Rs6323	G	62 (63.9%)	102 (53.4%)	0.088	0.64 (0.391–1.069)
	T	35 (36.1%)	89 (46.6%)	0.088	0.64 (0.391–1.069)
uVNTR	3.5R	64 (66.0%)	109 (58.0%)	0.190	0.71 (0.427–1.185)
	4.5R	33 (34.0%)	79 (42.0%)	0.190	0.71 (0.427–1.185)
	Allele/genotype	ADHD-girls	Control-girls	p-value ^a	OR (95% CI)
Rs6323	G	65 (61.3%)	152 (58.0%)	0.559	0.87 (0.549–1.393)
	T	41 (38.7%)	110 (42.0%)	0.559	0.87 (0.549–1.393)
	G/G	16 (30.2%)	48 (36.7%)	-	Reference
	G/T	33 (62.3%)	56 (42.7%)	0.114	1.77 (0.869–3.598)
	T/T	4 (7.5%)	27 (20.6%)	0.175	0.44 (0.135–1.465)
	p-value ^b	0.023 *	0.161
Dominant	G/G	16 (30.2%)	48 (36.6%)	0.400	0.75 (0.380–1.480)
	G/T+T/T	37 (69.8%)	83 (63.4%)	0.400	0.75 (0.380–1.480)
Recessive	G/G+G/T	49 (92.5%)	104 (79.4%)	0.022 *	0.31 (0.100–0.950)
	T/T	4 (7.5%)	27 (20.6%)	0.022 *	0.31 (0.100–0.950)
Over-dominant	G/G+T/T	20 (37.7%)	75 (57.2%)	0.016 *	2.21 (1.150–4.250)
	G/T	33 (62.3%)	56 (42.8%)	0.016 *	2.21 (1.150–4.250)
uVNTR	3.5R	62 (60.8%)	150 (59.5%)	0.826	1.05 (0.658–1.687)
	4.5R	40 (39.2%)	102 (40.5%)	0.826	1.05 (0.658–1.687)
	3.5R/3.5R	17 (33.3%)	48 (38.1%)	-	Reference
	3.5R/4.5R	28 (54.9%)	54 (42.9%)	0.296	0.68 (0.330–1.400)
	4.5R/4.5R	6 (11.8%)	24 (19.0%)	0.515	1.42 (0.490–4.060)
	p-value ^b	0.279	0.214
Dominant	3.5R/3.5R	17 (33.3%)	48 (38.1%)	0.550	0.81 (0.410–1.610)
	3.5R/4.5R+4.5R/4.5R	34 (66.7%)	78 (61.9%)	0.550	0.81 (0.410–1.610)
Recessive	3.5R/3.5R+3.5R/4.5R	45 (88.2%)	102 (81.5%)	0.230	1.76 (0.680–4.610)
	4.5R/4.5R	6 (11.8%)	24 (19.1%)	0.230	1.76 (0.680–4.610)
Over-dominant	3.5R/3.5R+4.5R/4.5R	23 (45.1%)	72 (57.1%)	0.150	0.62 (0.320–1.190)
	3.5R/4.5R	28 (54.9%)	54 (42.9%)	0.150	0.62 (0.320–1.190)

* p < 0.05; ^a The Chi-square p-value; ^b Hardy-Weinberg equilibrium p-value. The samples who have 2.5 or 5.5 repeats of uVNTR were excluded because of the small sample size.