Table 1.
Comparison of the different characteristics between patients from the Sun Yat-sen University Cancer Center and those from the Fujian Provincial Cancer Hospital’s cohort [14]
| Characteristics | Sun Yat-sen University Cancer Center patients cohort n (%) |
Fujian Provincial Cancer Hospital cohort n (%) |
|---|---|---|
| Total | 535 | 1197 |
| Age (years)a | ||
| Median (range) | 45 (20–72) | 46 (11–84) |
| Mean | 45.4 | 46.4 |
| The 8th AJCC/UICC clinical stage [cases (%)]a | ||
| III | 421 (78.7) | 381 (31.8) |
| IVa–b | 114 (21.3) | 462 (38.6) |
| GTVp (cm3)a | ||
| Median (range) | 33.8 (2.6–165.2) | 32.8 (0.1–235.6) |
| Mean | 41.0 | 41.2 |
| LDH (U/L)a | ||
| Median (range) | 165.4 (101.8–448.6) | 183 (106–751) |
| Mean | 171.3 | 193.4 |
| Sex | ||
| Male | 382 (71.4) | 905 (75.6) |
| Female | 153 (28.6) | 292 (24.4) |
| Histologyb | ||
| II | 27 (5.0) | 51 (4.3) |
| III | 508 (95.0) | 1134 (94.7) |
| The 8th AJCC/UICC T-classification | ||
| T1 | 22 (4.1) | 285 (23.8) |
| T2 | 45 (8.4) | 220 (18.4) |
| T3 | 389 (72.7) | 294 (24.6) |
| T4 | 79 (14.8) | 398 (33.2) |
| The 8th AJCC/UICC N-classification | ||
| N0 | 73 (13.6) | 174 (14.5) |
| N1 | 268 (50.1) | 658 (55.0) |
| N2 | 149 (27.9) | 270 (22.6) |
| N3 | 45 (8.4) | 95 (7.9) |
| The 7th AJCC/UICC T-classification | ||
| T1 | 22 (4.1) | NA |
| T2 | 43 (8.0) | NA |
| T3 | 325 (60.7) | NA |
| T4 | 145 (27.1) | NA |
| The 7th AJCC/UICC N-classification | ||
| N0 | 73 (13.6) | NA |
| N1 | 273 (51.0) | NA |
| N2 | 162 (30.3) | NA |
| N3a | 11 (2.1) | NA |
| N3b | 16 (3.0) | NA |
| The 7th AJCC/UICC clinical stage | ||
| III | 367 (68.6) | NA |
| IVa | 141 (26.4) | NA |
| IVb | 27 (5.0) | NA |
| EBV DNA (103 copies/mL)a | ||
| Median (range) | 1.65 (0–12,600) | NA |
| Mean | 97.9 | NA |
| EBV DNA (copies/mL)c | ||
| < 103 | 246 (46.0) | NA |
| 103–104 | 120 (22.4) | NA |
| 104–105 | 110 (20.6) | NA |
| 105–106 | 52 (9.7) | NA |
| ≥ 106 | 7 (1.3) | NA |
| Hb (g/L) | ||
| Median (range) | 143.0 (88.0–183.0) | 143 (80–171) |
| Mean | 141.6 | 143 |
| BMI (kg/m2) | ||
| Median (range) | 23.0 (15.2–39.7) | NA |
| Mean | 23.1 | NA |
| Chemotherapy | ||
| None | 0 (0.0) | 181 (15.1) |
| Concurrent | 535 (100.0) | NA |
| Other | 0 (0.0) | NA |
AJCC American Joint Committee on Cancer, UICC Union for International Cancer Control, GTVp gross primary tumor volume, LDH lactate dehydrogenase, NA not available, EBV DNA Epstein–Barr virus deoxyribonucleic acid, Hb hemoglobin, BMI body mass index
aCharacteristic included in Pan’s nomogram
bBased on the criteria of the WHO histological type (1991): II differentiated non-keratinizing carcinoma, III undifferentiated non-keratinizing carcinoma
cAs categorized in a previous study [26]