Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Sep 4;5:180183. doi: 10.1038/sdata.2018.183

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2018, The Author(s)

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ The Creative Commons Public Domain Dedication waiver http://creativecommons.org/publicdomain/zero/1.0/ applies to the metadata files made available in this article.

PMC Copyright notice

(a,b) Raw images of DRG explants (filenames ‘
27_0806d_0p2_003p000.tif
’ and ‘
24_2506d_0p3_003p000.tif
’ for a and b, respectively). The NGF gradient increases towards the top of the image. Scale bars 500 um. (c,d) Binary masks for the neurite regions of the images directly above. Superimposed is the Fourier approximation of radial outgrowth using five coefficients (red curve), and the outgrowth and bias measurements (text; lower right). Scale bars 500 um. (e) Quantification of average radial outgrowth by Fourier coefficient a₀ as a function of background concentration (x-axis) and gradient steepness (colours; see legend). (f) Quantification of outgrowth bias up the gradient by normalised coefficient b₁/a₀ Error bars are SEM.