Figure 7.

Regulation of autophagy of NSCLC cells by miR-21 via AMPK/ULK1 signaling pathway. (A) Activation of AMPK/ULK1 signaling pathway by miR-21. (B) ULK1 rescues the regulation of miR-21 on autophagy of A549 cells. Western blotting was used to determine the expression of ULK1, P-AMPKα, AMPKα, and LC3BII. The data were derived from the same membrane, and the membrane was stripped and re-probed. *P<0.05 compared with miR mimics-NC group; ^#P<0.05 compared with miR inhibitor-NC group. NC, negative control