Table 3.
Baseline features of the studies
| Studies | Age (years) | Males (%) | HBP (%) | DS (%) | DM (%) | CS (%) |
|---|---|---|---|---|---|---|
| DDC/C | DDC/C | DDC/C | DDC/C | DDC/C | DDC/C | |
| CURRENT OASIS 7 | 61.2/61.2 | 76.0/74.9 | 59.4/58.8 | 40.3/40.3 | 22.3/22.2 | 37.5/36.6 |
| OPTIMUS2007 | 64.0/59.0 | 60.0/70.0 | 90.0/95.0 | 90.0/95.0 | 100/100 | 15.0/20.0 |
| Khatri2013 | 64.0/62.0 | 100/8.00 | 81.0/91.0 | 100/97.0 | 73.0/61.0 | 69.0/61.0 |
| OPTIMUS3 | 61.3/61.3 | 68.6/68.6 | 94.3/94.3 | 94.3/94.3 | 100/100 | 20.0/20.0 |
| PRINCIPLE TIMI 44 | 63.8/64.0 | 77.8/71.6 | 77.8/85.3 | 86.9/90.2 | 29.3/32.4 | 16.2/17.6 |
| Tailor2014 | 63.0/63.0 | 82.7/74.1 | 82.7/74.1 | 88.5/83.3 | 34.6/29.6 | 67.3/77.8 |
| Chen2017 | 59.8/60.8 | 62.0/59.6 | 56.0/56.1 | 26.0/28.1 | 30.0/31.6 | 38.0/35.1 |
| Wu2017 | 62.7/60.4 | 70.0/75.0 | 70.0/50.0 | 60.0/80.0 | 30.0/45.0 | 30.0/55.0 |
| ACCEL AMI | 61.1/62.7 | 76.7/71.7 | 36.7/46.7 | 46.7/36.7 | 20.0/21.7 | 73.3/61.7 |
| ACCEL DM | 62.0/64.0 | 66.7/70.7 | 64.1/75.6 | 33.3/34.1 | 100/100 | 43.6/41.5 |
| CREATIVE | 58.1/58.5 | 61.0/59.3 | 61.0/65.8 | 68.5/64.5 | 32.0/33.8 | 38.2/36.5 |
| Ha2013 | 62.3/64.9 | 71.4/67.7 | 76.1/71.4 | 42.5/33.3 | 100/100 | 23.8/23.8 |
| HOST ASSURE | 63.7/62.8 | 67.0/69.8 | 68.6/66.8 | 62.7/64.2 | 31.3/31.8 | 30.8/32.8 |
| Jeong2009 | 63.0/63.0 | 66.7/66.7 | 50.0/53.3 | 20.0/20.0 | 16.7/30.0 | 60.0/36.7 |
Abbreviations: DDC: double dose clopidogrel, C: control group, HBP: high blood pressure, DS: dyslipidemia, DM: diabetes mellitus, CS: current smoker