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. 2018 Sep 3;6:57. doi: 10.1186/s40560-018-0322-8

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Patient inclusion flow chart. Data for 3195 patients were reviewed and 495 patients did not meet inclusion criteria. There were data deficits for 205 patients, leaving a final study group of 2495 patients. The number of patients with missing data is not considered regarding duplication. PT-INR: prothrombin time international normalized ratio; WBC: white blood cell; SOFA score: Sequential Organ Failure Assessment score