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. 2018 Aug 23;19:179–189. doi: 10.1016/j.redox.2018.08.012

Fig. 7.

Fig. 7

Higher expression of DNMT1 in the lens epithelium of HMC and increased expression of GSTP1 and TXNRD2 in LECs after treatment with 5-Aza. (A) qPCR results showed that the mRNA level of DNMT1 was higher in HMC lens epithelium than in the ARC group. n = 8 independent experiments. (B) ELISA results showed that protein level of DNMT1 was higher in HMC lens epithelium than in ARC samples. n = 5 independent experiments. (C) qPCR results showed that mRNA levels of both GSTP1 and TXNRD2 in cultured LECs increased significantly after treatment with 5-Aza. n = 3 independent experiments. (D) Western blot assay results showed that protein levels of both GSTP1 and TXNRD2 increased in cultured LECs after treatment with 5-Aza. mean ± SD, unpaired two-tailed Student's t-test, *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001.