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. 2018 Aug 24;14:2220–2228. doi: 10.3762/bjoc.14.196

Table 5.

Batch vs flow study of the dehydrochlorination step.

graphic file with name Beilstein_J_Org_Chem-14-2220-i005.jpg

entry product mode tres (h) conversion (%)a

1 Inline graphic
19
batch
flow
1
2
83
100
2 Inline graphic
20
batch
flow
flow
1
2
3
100
88
99
3 Inline graphic
21
batch
flow
18
2
84
19

aMeasured by 1H NMR spectroscopy.