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. 2018 Jul 23;16(3):2471–2477. doi: 10.3892/etm.2018.6508

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Copyright: © Dai et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 1. — Flow cytometry analysis of proportions of circulating TFH cells in patients with cITP and HCs. (A) CD4⁺ lymphocytes were gated and the CD4⁺ CXCR5⁺ICOS⁺ T subsets were gated using flow cytometry. Plots in the inter box of D⁺⁺ represent circulating TFH cells. (B) Circulating TFH in healthy controls, (C) circulating TFH in cITP patient responders at pre-treatment, (D) circulating TFH in cITP patient responders at post-treatment, (E) circulating TFH in cITP patient non-responders at pre-treatment and (F) circulating TFH cITP patient non-responders at post-treatment were indicated. (G) Bar graph quantification of circulating TFH cells in HCs and patients with cITP. (H) Bar graph quantification of circulating TFH cells in patient responders and non-responders. Normalized values were presented as the mean ± standard deviation. *P<0.05 as indicated. TFH, T follicular helper; HCs, healthy controls; cITP, chronic immune thrombocytopenia.