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. 2018 Sep 3;16:246. doi: 10.1186/s12967-018-1623-3

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Mean LEFS change score at every post-treatment time-point. Scores were significantly higher than baseline at all time-points. MCID = 9 which is represented by horizontal line. *p < 0.05 compared to 1-month scores; **p < 0.05 compared to 1- and 3-month scores. Number of patients reporting at each time point: 1 month (N = 14); 3 month (N = 19); 6 month (N = 19); 12 month (N = 19); 18 month (N = 16); 24 month (N = 17); 36 month (N = 8)