Table 2. . Basic terminology used to describe melanocytic lesions.

Layer	Terminology	Description
Superficial (suprabasal) epidermis	Regular honeycomb pattern	Normal keratinocytes appearing as polygonal cells with well-demarcated refractive cellular outlines
	Regular cobblestone pattern	Small monomorphous round cells appearing bright because of a high amount in melanin in the keratinocytes
	Irregular (or atypical) honeycomb or cobblestone pattern	Irregular-shaped keratinocytes in a honeycomb or cobblestone pattern
	Broadened honeycomb pattern	Honeycomb pattern with enlarged intercellular spaces
	Epidermal disarray (or disarranged pattern)	No recognizable honeycomb or cobblestone pattern replaced by irregular bright particles
	Pagetoid cells (or pagetoid infiltration)	Cells twice the size of keratinocytes. May be round, dendritic or both
Basal cell layer and DEJ	Edged papillae	Normal dermal papillae surrounded by a rim of refractive cells
	Nonedged dermal papillae	Dermal papillae are not visible or not demarcated by a normal rim of bright cell but rather by large reflective structures
	DEJ disarray	Loss of the normal architecture of the DEJ
	Nests	Oval to round bright structures corresponding to aggregates of melanocytes. Nests may be further descried as being dense, sparse or cerebriform

DEJ: Dermoepidermal junction.