Table 7. . Reflectance confocal microscopy features of lentigo maligna and lentigo maligna melanoma.

Layer	Feature	Description
Suprabasal epidermis	Large round pagetoid cells	Round bright nucleated cells twice the size of keratinocytes in the suprabasal epidermis
	Epidermal disarray	No recognizable honeycomb or cobblestone pattern
	Atypical cobblestone pattern	Loss of normal cobblestone pattern with atypical cell size and/or refractivity
Basal cell layer and DEJ	Nonedged papillae	Loss of normal rim of bright cells around the dermal papillae
	Atypical cells at the junction	Including cells distributed in sheet-like structures
	Follicular localization of atypical cells	Atypical cells around the hair follicles
	Medusa head-like structures	Elongated bundles, composed of atypical cells, extending from the hair follicles
Upper dermis	Large nucleated cells in the dermal papillae	–
	Dermal nests	Aggregation of cells
	Plump bright cells	Bright refractive particles with no visible nucleus; represent melanophages on histopathology

DEJ: Dermoepidermal junction.