Table 5.
Differences in M. tuberculosis characteristics between the Beijing and non-Beijing families
| Drug susceptibility testing | total (n = 668) | Beijing family isolates(n = 558) | Non-Beijing family isolates (n = 110) | OR | 95% CI | p-value |
|---|---|---|---|---|---|---|
| Pan sensitive | 466 | 394 | 72 | 1.09 | 0.69–1.75 | 0.700 |
| Any resistance to | ||||||
| Isoniazid | 99 | 85 | 14 | 1.23 | 0.67–2.26 | 0.487 |
| Rifampin | 63 | 54 | 9 | 1.20 | 0.57–2.51 | 0.623 |
| Ethambutol | 42 | 38 | 4 | 1.56 | 0.54–4.50 | 0.415 |
| Streptomycin | 129 | 108 | 21 | 1.01 | 0.65–1.71 | 0.946 |
| Kanamycin | 28 | 20 | 8 | 2.11 | 0.90–4.92 | 0.078 |
| ofloxacin | 58 | 44 | 14 | 1.79 | 0.94–3.41 | 0.072 |
| All four first-line drugs resistance | 30 | 29 | 1 | 5.97 | 1.05–44.33 | 0.045 |
| MDR-TB | 50 | 47 | 3 | 3.28 | 1.01–10.37 | 0.038 |
| Pre-XDR-TB | 17 | 16 | 1 | 3.21 | 0.42–24.51 | 0.332 |
| XDR-TB | 11 | 10 | 1 | 1.99 | 0.25–15.69 | 1.001 |
OR odds ratio, CI confidence interval
MDR-TB: multi-drug resistance TB, resistant to at least isoniazid and rifampicin
XDR-TB: extensively drug-resistant tuberculosis, MDR-TB plus resistance to ofloxacin and kanamycin
Pre-XDR-TB: MDR-TB plus resistance to either ofloxacin or kanamycin
First-line drugs resistance: resistant to isoniazid, rifampin, ethambutol and streptomycin