Table 2.
Distribution of allelic frequencies of SNPs in cases and controls (n, %)
| SNPs | Allele (major:minor) |
Control (243) | Case (243) | OR(95%CI) | p | p FDR | ||
|---|---|---|---|---|---|---|---|---|
| major | minor | major | minor | |||||
| rs174546 | C:T | 324(67.8) | 154(32.2) | 328(68.3) | 152(31.7) | 0.98(0.75–1.29) | 0.855 | 0.916 |
| rs174585 | G:A | 440(90.9) | 44(9.1) | 452(93.0) | 34(7.0) | 0.75(0.47–1.20) | 0.230 | 0.493 |
| rs498793 | C:T | 444(92.5) | 36(7.5) | 444(92.1) | 38(7.9) | 1.07(0.66–1.72) | 0.823 | 1.029 |
| rs174602 | T:C | 360(75.9) | 114(24.1) | 375(77.5) | 109(22.5) | 0.94(0.70–1.28) | 0.575 | 0.958 |
| rs174593 | T:C | 440(90.5) | 46(9.5) | 451(92.8) | 35(7.2) | 0.73(0.46–1.16) | 0.202 | 0.505 |
| rs526126 | C:G | 275(56.6) | 211(43.4) | 315(69.4) | 139(30.6) | 0.55(0.42–0.72) | < 0.001 | < 0.05* |
| rs174616 | G:A | 412(84.8) | 74(15.2) | 414(85.5) | 70(14.5) | 0.93(0.65–1.33) | 0.738 | 1.107 |
| rs17606561 | G:A | 380(78.5) | 104(21.5) | 360(74.1) | 126(25.9) | 1.31(0.97–1.77) | 0.104 | 0.390 |
| rs2236212 | C:G | 318(66.8) | 158(33.2) | 317(66.3) | 161(33.7) | 1.01(0.77–1.32) | 0.873 | 0.873 |
| rs3798712 | A:G | 365(76.7) | 111(23.3) | 374(77.3) | 110(22.7) | 0.94(0.69–1.27) | 0.828 | 0.955 |
| rs953413 | A:G | 436(90.5) | 46(9.5) | 415(88.3) | 55(11.7) | 1.28(0.84–1.93) | 0.280 | 0.525 |
| rs3756963 | T:C | 373(77.1) | 111(22.9) | 354(72.8) | 132(27.2) | 1.28(0.96–1.72) | 0.129 | 0.387 |
| rs10498676 | G:A | 263(55.0) | 215(45.0) | 289(60.7) | 187(39.3) | 0.79(0.61–1.02) | 0.075 | 0.375 |
| rs6936315 | T:C | 339(71.2) | 137(28.8) | 349(72.1) | 135(27.9) | 0.92(0.70–1.23) | 0.760 | 1.036 |
| rs9468304 | A:G | 329(68.0) | 155(32.0) | 299(61.5) | 187(38.5) | 1.37(1.05–1.79) | 0.035 | 0.263 |
Major major allele, minor minor allele, OR Odds ratio, CI confidence interval, FDR false discovery rate, pFDR FDR corrected p value, * p < 0.05