Table 3.
SNPs | Model | genotype | Control (243) | Case (243) | OR (95% CI) | p | p FDR |
---|---|---|---|---|---|---|---|
rs174546 | overdominant | C/C-T/T | 133 (55.6) | 136 (56.7) | 1.00 | 0.82 | 0.82 |
T/C | 106 (44.4) | 104 (43.3) | 0.96 (0.67–1.38) | ||||
rs174585 | dominant | G/G | 199 (82.2) | 210 (86.4) | 1.00 | 0.2 | 0.375 |
A/G-A/A | 43 (17.8) | 33 (13.6) | 0.73 (0.44–1.19) | ||||
rs498793 | overdominant | C/C-T/T | 210 (87.5%) | 207 (85.9%) | 1.00 | 0.6 | 0.75 |
T/C | 30 (12.5%) | 34 (14.1%) | 1.15 (0.68–1.95) | ||||
rs174602 | overdominant | T/T-C/C | 145 (61.2) | 157 (64.9) | 1.00 | 0.4 | 0.667 |
C/T | 92 (38.8) | 85 (35.1) | 0.85 (0.59–1.24) | ||||
rs174593 | recessive | T/T-C/T | 241 (99.2) | 243 (100) | 1.00 | 0.095 | 0.204 |
C/C | 2 (0.8) | 0 (0) | NA | ||||
rs526126 | recessive | C/C-G/C | 203 (83.5) | 224 (98.7) | 1.00 | < 0.0001 | < 0.01* |
G/G | 40 (16.5) | 3 (1.3) | 0.07 (0.02–0.22) | ||||
rs174616 | overdominant | G/G-A/A | 181 (74.5) | 188 (77.7) | 1.00 | 0.41 | 0.615 |
A/G | 62 (25.5) | 54 (22.3) | 0.84 (0.55–1.27) | ||||
rs17606561 | overdominant | G/G-A/A | 164 (67.8) | 137 (56.4) | 1.00 | 0.0096 | 0.036* |
A/G | 78 (32.2) | 106 (43.6) | 1.63 (1.12–2.36) | ||||
rs2236212 | recessive | C/C-G/C | 212 (89.1) | 210 (87.9) | 1.00 | 0.68 | 0.729 |
G/G | 26 (10.9) | 29 (12.1) | 1.13 (0.64–1.98) | ||||
rs3798712 | overdominant | A/A-G/G | 151 (63.5) | 160 (66.1) | 1.00 | 0.54 | 0.736 |
G/A | 87 (36.5) | 82 (33.9) | 0.89 (0.61–1.29) | ||||
rs953413 | recessive | A/A-G/A | 241 (100) | 232 (98.7) | 1.00 | 0.039 | 0.098 |
G/G | 0 (0) | 3 (1.3) | NA | ||||
rs3756963 | overdominant | T/T-C/C | 161 (66.5) | 133 (54.7) | 1.00 | 0.0078 | 0.039* |
C/T | 81 (33.5) | 110 (45.3) | 1.64 (1.14–2.37) | ||||
rs10498676 | recessive | G/G-A/G | 184 (77) | 204 (85.7) | 1.00 | 0.014 | 0.042* |
A/A | 55 (23) | 34 (14.3) | 0.56 (0.35–0.89) | ||||
rs6936315 | overdominant | T/T-C/C | 141 (59.2) | 149 (61.6) | 1.00 | 0.6 | 0.692 |
C/T | 97 (40.8) | 93 (38.4) | 0.91 (0.63–1.31) | ||||
rs9468304 | overdominant | A/A-G/G | 143 (59.1) | 110 (45.3) | 1.00 | 0.0023 | 0.017* |
G/A | 99 (40.9) | 133 (54.7) | 1.75 (1.22–2.50) |
OR Odds ratio, CI confidence interval, pFDR FDR corrected p value,* p < 0.05, NA is not applicable