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. 2018 Sep 4;18:148. doi: 10.1186/s12890-018-0715-4

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Gene-expression profiles after exposure to CSE in SAECs and NHBEs. Two different batches of SAECs and NHBEs were used. Cells were exposed to 2.5% CSE for 24 h or not (controls). Scatter plot of (a) NHBEs and (b) SAECs. The vertical axis represents the relative signal intensity in CSE-exposed cells, and the horizontal axis represents the control (without CSE exposure). Both axes show log scales. c Venn diagram of probes showing significant upregulation in SAECs and NHBEs after CSE exposure. d Venn diagram of probes showing significant downregulation in SAECs and NHBEs after CSE exposure. CSE, cigarette smoke extract; SAECs, small airway epithelial cells; NHBEs, normal human bronchial epithelial cells.