Table 1.

Overrepresented pathways in SAECs based on KEGG analysis

Pathway	p	Genes
Rheumatoid arthritis	<  0.001	CCL20, MMP1, IL1B, TLR2, FOS, IL8
TNF-signaling pathway	0.001	CCL20, PTGS2, IL1B, MAP3K8, FOS, TRAF1
Toll-like receptor-signaling pathway	0.001	SPP1, IL1B, MAP3K8, TLR2, FOS, IL8
Leishmaniasis	0.001	NCF1, PTGS2, IL1B, TLR2, FOS
Malaria	0.004	CSF3, IL1B, TLR2, IL8
Amoebiasis	0.005	IL1B, IL1R2, TLR2, IL8, SERPINB2
NF-κB-signaling pathway	0.020	PTGS2, IL1B, TRAF1, IL8
MAPK-signaling pathway	0.026	NR4A1, PLA2G4A, IL1B, IL1R2, MAP3K8, FOS
Chagas disease (American trypanosomiasis)	0.032	IL1B, TLR2, FOS, IL8

SAECs small airway epithelial cells, KEGG Kyoto Encyclopedia of Genes and Genomes