Table 1. Health impact of the current girls-only vaccination program and alternative vaccination strategies on cervical disease per 100,000 women.
The relative lifetime change as compared to no vaccination are shown between parentheses. In the alternative vaccination strategies, boys, and adult women and men are included in the vaccination strategies in addition to girls. Vaccination at STI consultations for adult males and females also includes routine vaccination for boys.
| Strategy | False-positive referrals | CIN 1 | CIN 2 | CIN 3 | Clinically detected cases | Screen-detected cancers | Cervical cancer deaths | Life years lost |
|---|---|---|---|---|---|---|---|---|
| No vaccination | 543 | 2,473 | 1,655 | 2,413 | 444 | 136 | 193 | 3,089 |
| Current program (60% cov.) | 458 (-16%) | 2,121 (-14%) | 1,361 (-18%) | 1,778 (-26%) | 289 (-35%) | 83 (-39%) | 126 (-34%) | 1,979 (-36%) |
| Improved coverage among girls | ||||||||
| Girls (80% cov.) | 448 (-17%) | 2,061 (-17%) | 1,318 (-20%) | 1,696 (-30%) | 256 (-42%) | 76 (-44%) | 110 (-43%) | 1,772 (-43%) |
| Girls (100% cov.) | 431 (-21%) | 2,006 (-19%) | 1,276 (-23%) | 1,619 (-33%) | 215 (-52%) | 70 (-49%) | 92 (-52%) | 1,555 (-50%) |
| Inclusion of also boys and adults | ||||||||
| Boys (60% cov.) | 443 (-18%) | 2,037 (-18%) | 1,310 (-21%) | 1,682 (-30%) | 246 (-45%) | 74 (-46%) | 105 (-45%) | 1,715 (-44%) |
| Boys (80% cov.) | 430 (-21%) | 1,976 (-20%) | 1,258 (-24%) | 1,596 (-34%) | 201 (-55%) | 67 (-51%) | 85 (-56%) | 1,469 (-52%) |
| Boys (100% cov.) | 416 (-23%) | 1,922 (-22%) | 1,222 (-26%) | 1,526 (-37%) | 168 (-62%) | 60 (-56%) | 70 (-64%) | 1,285 (-58%) |
| STI consultations (F) | 454 (-16%) | 2,093 (-15%) | 1,336 (-19%) | 1,732 (-28%) | 274 (-38%) | 80 (-42%) | 119 (-38%) | 1,885 (-39%) |
| STI consultations (F+M) | 438 (-19%) | 2,004 (-19%) | 1,286 (-22%) | 1,631 (-32%) | 231 (-48%) | 70 (-49%) | 98 (-49%) | 1,621 (-48%) |
CIN = cervical intraepithelial neoplasia; cov. = coverage; STI = sexually transmitted infections; F = females; M = males