Table 1.
Results (mean±SD, n=3) of clot-based assays utilizing SECS solutions (c=0.1 mg/mL) and SECSBES@Ag suspensions (c=0.1 mg/mL) added to blood plasma samples
| Sample | aPTT (seconds) | PT (seconds) |
|---|---|---|
| PL | 25.87±0.31 | 10.80±0.10 |
| PL+25 μL SECSVS | 28.70±0.10 | 10.20±0.21 |
| PL+50 μL SECSVS | 29.20±0.20 | 10.85±0.30 |
| PL+25 μL SECSBES | 37.60±0.10 | 11.67±0.18 |
| PL+50 μL SECSBES | 30.20±0.10 | 11.70±0.10 |
| PL+25 μL SECSBES@Ag | 62.50±0.30 | 12.67±0.18 |
| PL+50 μL SECSBES@Ag | 132.60±0.80 | 12.78±0.07 |
Abbreviations: aPTT, activated partial thromboplastin time; PL, blood plasma; PT, prothrombin time; SECSVS or SECSBES, sulfoethyl chitosan synthesized with sodium vinyl sulfonate or sodium 2-bromoethanesulfonate, respectively; SECSBES@Ag, silver nanoparticles capped with SECSBES.