Table 2.
Results (mean±SD, n=3) of Xa determination assay utilizing SECS solutions (c=0.1 mg/mL) and SECSBES@Ag suspensions (c=0.1 mg/mL), added to blood plasma samples
| Sample | Chromogenic Xa testing | PT-based Xa testing (% dN) | PT-based Xa testing (seconds) |
|---|---|---|---|
| PL+ ultrapure water | NA | 56.50±0.20 | 39.75±0.25 |
| PL+SECSVS | 0 | 31.80±0.10 | 46.59±0.25 |
| PL+SECSBES | 0 | 33.00±0.10 | 45.37±0.12 |
| PL+SECSBES@Ag | 0 | 25.80±0.05 | 52.75±0.24 |
Abbreviations: PL, blood plasma; PT, prothrombin time; SECSVS or SECSBES, sulfoethyl chitosan synthesized with sodium vinyl sulfonate or sodium 2-bromoethane-sulfonate, respectively; SECSBES@Ag, silver nanoparticles capped with SECSBES.