Table S1.
The proportion of each phase of cell cycle in BxPC-3 and SW1990 cell lines
| Group | BxPC-3
|
SW1990
|
||||
|---|---|---|---|---|---|---|
| G0–G1 phase (%) | S phase (%) | G2–M phase (%) | G0–G1 phase (%) | S phase (%) | G2–M phase (%) | |
| Control | 57.99 ± 1.22 | 30.58 ± 0.60 | 11.43 ± 0.78 | 49.93 ± 1.86 | 37.44 ± 1.46 | 12.63 ± 3.18 |
| NBMPR | 57.29 ± 0.95 | 31.55 ± 1.18 | 11.16 ± 0.94 | 50.34 ± 1.40 | 36.76 ± 1.01 | 12.89 ± 1.95 |
| GEM | 74.68 ± 1.64 | 24.12 ± 1.44 | 1.20 ± 0.24 | 62.50 ± 0.94 | 37.48 ± 0.94 | 0.02 ± 0.01 |
| GEM + NBMPR | 61.35 ± 1.30 | 28.16 ± 1.49 | 10.49 ± 0.85 | 53.57 ± 1.16 | 37.44 ± 1.25 | 8.99 ± 0.72 |
| GEM-C14 | 76.28 ± 1.05 | 22.66 ± 1.22 | 1.06 ± 0.27 | 61.77 ± 1.72 | 37.92 ± 1.41 | 0.31 ± 0.54 |
| GEM-C14 + NBMPR | 74.39 ± 1.29 | 24.67 ± 1.47 | 0.94 ± 0.28 | 61.36 ± 2.91 | 38.61 ± 2.91 | 0.03 ± 0.01 |
| GEM-HSA-NP | 75.16 ± 1.74 | 23.57 ± 1.45 | 1.27 ± 0.41 | 62.85 ± 1.29 | 37.01 ± 1.29 | 0.14 ± 0.01 |
| GEM-HSA-NP + NBMPR | 76.04 ± 1.57 | 22.92 ± 1.41 | 1.04 ± 0.26 | 66.64 ± 1.24 | 33.35 ± 1.24 | 0.01 ± 0.00 |
Note: Data are expressed as mean ± SD.
Abbreviations: GEM, gemcitabine; GEM-C14, 4-N-myristoyl-gemcitabine; GEM-HSA-NP, gemcitabine-loaded human serum albumin nanoparticle; NBMPR, S-(4-nitrobenzyl)-6-thioinosine.