Table 2.
Clinical and laboratory characteristics, according to iron and ferritin tertiles
| Clinical presentation | Population n = 280 | 1st iron tertile (≤ 40 mcg/dL) | 2nd iron tertile (> 40 or ≤ 67 mcg/dL) | 3rd iron tertile (> 67 mcg/dL) | p value | 1st ferritin tertile (≤ 110 ng/mL) | 2nd ferritin tertile (>110 or ≤ 219 ng/mL) | 3rd ferritin tertile (> 219 ng/mL) | p value |
|---|---|---|---|---|---|---|---|---|---|
| Killip Class I | 244 (87) | 74 (27) | 83 (30) | 87 (31) | 0.12 | 73 (26) | 88 (31.4) | 78 (28) | 0.23 |
| Killip Class II | 18 (6.4) | 11 (4) | 4 (1.4) | 3 (1) | 14 (5) | 2 (0.7) | 2 (0.7) | ||
| Killip Class III | 11 (3.9) | 4 (1.4) | 4 (1.4) | 3 (1) | 3 (1) | 2 (0.7) | 6 (2.1) | ||
| Killip Class IV | 7 (2.5) | 6 (2.1) | 4 (1.4) | 0 | 2 (0.7) | 2 (0.7) | 3 (1) | ||
| Ejection fraction classification | |||||||||
| LVEF > 50% | 157 (69) | 42 (15) | 58 (21) | 57 (20) | 0.08 | 43 (15) | 59 (21) | 54 (19) | 0.7 |
| LVEF 41-50% | 23 (10) | 16 (6) | 3 (1) | 4 (1.4) | 7 (2.5) | 9 (3) | 7 (2.5) | ||
| LVEF 30-40% | 38 (17) | 16 (6) | 14 (5) | 8 (3) | 16 (6) | 8 (3) | 11 (4) | ||
| LVEF < 30% | 11 (5) | 4 (1.4) | 4 (1.4) | 3 (1) | 6 (2.1) | 2 (0.7) | 3 (1) | ||
| Laboratory assessment | |||||||||
| Creatinine, mg/dL | 1.08 ± 0.9 | 1.2 ± 1.2 | 1.05 ± 0.6 | 0.9± 1.8 | 0.9 | 1.1 ± 0.7 | 1 ± 0.6 | 1.1 ± 1.2 | 0.8 |
| BNP, pg/mL | 331.6 ± 499 | 567 ± 712 | 266 ± 371 | 180 ± 212 | < 0.001 | 488 ± 684 | 204 ± 270 | 346 ± 427 | 0.001 |
| Hemoglobin, g/dL | 13.1 ± 2 | 11.8 ± 2.2 | 13.4 ± 2 | 14 ± 16 | < 0.001 | 12 ± 2.2 | 14 ± 1.7 | 14 ± 2 | <0.001 |
Results expressed as n (%) or mean ± median. LVEF: left ventricular ejection fraction; BNP: brain natriuretic peptide.