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. Author manuscript; available in PMC: 2018 Sep 4.
Published in final edited form as: Exp Neurol. 2016 Jul 14;285(Pt B):147–158. doi: 10.1016/j.expneurol.2016.07.005

Fig. 3.

Fig. 3.

Effect of intravesical infusion of OXO-M (50 μM) on reflex bladder activity in a conscious spinal cord injured cat. A. Control saline CMG. Arrow indicates the start of infusion (2 ml/min). * indicates the first micturition contraction. B. Infusion of OXO-M reduces BC, increases MMP and increases the frequency and amplitude of pre-micturition contractions (PMCs). C. Intravesical infusion of atropine methyl nitrate (AMN, 50 μM) reverses the excitatory effect of OXO-M on PMCs and increases BC. D. Subsequent intravesical infusion of AMN (50 μM) in combination with OXO-M suppresses the facilitatory effect of OXO-M on BC and PMCs. All recordings are from the same experiment.