Table 1.
Parameters | Saline | Saline | OXO-M (50 μM) |
---|---|---|---|
BC (ml) | 71.4 ± 7.56 | 74.1 ± 7.95 | 44.1 ± 5.12** |
MMP (cm H2O) | 40.4 ± 3.94 | 40.0 ± 4.50 | 56.8 ± 5.83* |
PMC-AUC (cm H2O·sec) | 998.2 ± 111.1 | 1030 ± 130.0 | 1636 ± 247.2* |
Data are shown as mean ± standard error of the mean. Data are from 13 experiments for bladder capacity (BC) and maximum micturition pressure (MMP) and from 12 experiments for pre-micturition contraction–area under curve (PMC-AUC). Statistical significance was tested using repeated-measures ANOVA followed by Bonferroni’s multiple comparison test. Asterisks represent significant changes (*p < 0.05, **p < 0.001) between the first saline control values and the oxotremorine-M (OXO-M) values. The values for the two saline controls were not significantly different (p > 0.05).