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. Author manuscript; available in PMC: 2018 Sep 4.
Published in final edited form as: Exp Neurol. 2016 Jul 14;285(Pt B):147–158. doi: 10.1016/j.expneurol.2016.07.005

Table 2.

The effect of 8-OH-DPAT on the responses to intravesical administration of OXO-M.

Parameters Saline OXO-M (50 μM) 8-OH-DPAT (0.5 mg/kg) OXO-M (50 μM)
BC (ml) 68.2 ± 7.66 38.6 ± 6.5 87.4 ± 15.0a 53.8 ± 9.79
MMP (cm H2O) 52.7 ± 7.92 72.8 ± 9.85b,d 53.0 ± 6.17 75.8 ± 8.01c,d
PMC-AUC (cm H2O·sec) 1620 ± 564.3 2218 ± 450.4 1409 ± 68.8 3774 ± 383.3c,e,f

Data are shown as mean ± standard error of the mean. Data are from 5 experiments for bladder capacity (BC), maximum micturition pressure (MMP), and pre-micturition contraction– area under curve (PMC-AUC). Statistical significance was tested using repeated-measures ANOVA followed by Bonferroni’s multiple comparison test.

(a)

indicates significant difference (p < 0.01) from first OXO-M value.

(b)

indicates significant difference (p < 0.05) from saline.

(c)

indicates significant difference (p < 0.01) from saline.

(d)

indicates significant difference (p < 0.05) from 8-OH-DPAT.

(e)

indicates significant difference (p < 0.05) from first OXO-M.

(f)

indicates significant difference (p < 0.01) from 8-OH-DPAT.