Table 4.
Haplotype analysis of rs599839, rs646776 and rs12740374 in the patients with type 2 diabetes mellitus group and peripheral artery disease patients with type 2 diabetes mellitus group
| Haplotype | DM + PAD (freq) | DM (freq) | χ2 | P | OR | 95% CI |
|---|---|---|---|---|---|---|
| AAG | 840.97 (0.956) | 819.95 (0.928) | 6.333 | 0.011* | 1.683 | 1.118–2.535 |
| GAG | 11.03 (0.013) | 14.05 (0.016) | 0.355 | 0.551 | 0.786 | 0.335–1.739 |
| GGG | 3.00 (0.003) | 1.01 (0.001) | 1.005 | 0.316 | 3.005 | 0.313–28.822 |
| GAT | 1.00 (0.001) | 3.00 (0.003) | 0.797 | 0.372 | 0.333 | 0.049–2.263 |
| AGT | 2.03 (0.002) | 3.05 (0.003) | 0.203 | 0.652 | 0.666 | 0.112–3.947 |
| GGT | 21.97 (0.025) | 42.94 (0.049) | 6.934 | 0.008** | 0.502 | 0.297–0.846 |
Haplotypes were constructed for: rs12740374, rs646776 and rs599839. *P < 0.05, **P < 0.01. CI, confidence interval; DM, patients with type 2 diabetes mellitus; DM + PAD, peripheral artery disease patients with type 2 diabetes mellitus; freq, frequency; OR, odds ratio.