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. 2018 Sep 5;38(5):BSR20181023. doi: 10.1042/BSR20181023

Figure 3. Effect of ZNF139-siRNA on ZNF139, miR-185 expression and chemosensitivity of SGC7901/ADR cells.

Figure 3

Expression of ZNF139 were identified by Western blot as well as qRT-PCR ((A) for different doses and (B) for different times). Then chemosensitivity to ADR, 5-FU, L-OHP were tested in ZNF139-siRNA group, NS-siRNA group (C). The expression of ZNF139 was remarkably increased in SGC7901 after transfecting with pcDNA-ZNF139 48 h later (P<0.05) (D). Chemosensitivity to ADR, 5-FU, L-OHP in Vector group and pcDNA group was shown as in (E). *P<0.01 compared with NS-siRNA group, Vector group, control group.