Figure 4. Effect of miR-185 mimics on miR-185, ZNF139 expression and chemosensitivity of SGC7901/ADR cells.

Cells were transfected with miR-185 mimics or Mock, and the expression of miR-185 was tested with qRT-PCR (A) and chemosensitivity to ADR, 5-FU, L-OHP were tested in miR-185 mimics group, control group (B). Anti-miR-185 was transfected into SGC7901/ADR cells, and variation of chemosensitivity was detected with MTT (C). *P<0.01 compared with Mock group, control group.