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. 2018 Sep 5;38(5):BSR20181023. doi: 10.1042/BSR20181023

Figure 5. Effect of ZNF139 on the transcription of miR-185 in SGC7901 cells.

Figure 5

Expression of miR-185 were tested with qRT-PCR after ZNF139 was inhibited in SGC7901/ADR cells (A). Meanwhile, there was no remarkable change in the expression of ZNF139 in SGC7901/ADR after transfection ((B,C) qRT-PCR and Western blot). After transfection with pcDNA-ZNF139, the expression of miR-185 was detected (D). The expression levels of miR-185 were affected by the concentration of ZNF139 transfection through the luciferase assays (E). ChIP showed the physical interaction between ZNF139 and miR-185 (F). *P<0.01 compared with Vector group, control group.