Table 2. The prognostic value of PRDX1 mRNA expression in ovarian cancer.
Overall survival | Progress-free survival | |||||
---|---|---|---|---|---|---|
Cases | HR (95% CI) | P-value | Cases | HR (95% CI) | P-value | |
Histology | ||||||
All cancer patients | 1656 | 1.09 (0.96–1.25) | 0.19 | 1435 | 1.07 (0.94–1.21) | 0.31 |
Serous cancer patients | 1207 | 1.15 (0.98–1.36) | 0.092 | 1104 | 0.91 (0.78–1.06) | 0.24 |
Endometrioid cancer patients | 37 | 2.1 (0.35–12.6) | 0.41 | 51 | 0.3 (0.07–1.29) | 0.086 |
Pathological grades | ||||||
I | 56 | 0.25 (0.09–0.7) | 0.0044* | 37 | 0.14 (0.04–0.42) | 5.4e−05* |
II | 324 | 0.71 (0.52–0.97) | 0.028* | 256 | 0.75 (0.53–1.05) | 0.094 |
III | 1015 | 0.92 (0.75–1.12) | 0.4 | 837 | 0.91 (0.77–1.09) | 0.3 |
Clinical stages | ||||||
I and II | 135 | 0.52 (0.18–1.5) | 0.22 | 163 | 2.12 (1.06–4.27) | 0.03* |
III and IV | 1220 | 1.15 (0.98–1.35) | 0.084 | 1081 | 0.89 (0.76–1.04) | 0.15 |
Chemotherapy | ||||||
Contains Platin | 1409 | 0.91 (0.77–1.07) | 0.26 | 1259 | 1.08 (0.95–1.23) | 0.24 |
Contains Taxol | 793 | 1.17 (0.96–1.41) | 0.12 | 715 | 0.9 (0.76–1.07) | 0.23 |
Contains Taxol+Platin | 776 | 1.16 (0.95–1.41) | 0.14 | 698 | 0.9 (0.75–1.07) | 0.24 |
*P<0.05.